Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CAP1
  • Mouse genes Cap1
  • Rat genes Cap1
  • Zfish genes cap1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cap1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CAP1	IPI	UniProtKB:Q2GHU2	Human	PMID:19273555
Molecular Function	GO:0005515	protein binding	Cap1	IPI	UniProtKB:Q99N72	Mouse	MGI:MGI:3688344|PMID:15102471
Cellular Component	GO:0030864	cortical actin cytoskeleton	Cap1	IDA		Mouse	PMID:15004221
Cellular Component	GO:0005737	cytoplasm	Cap1	IDA		Mouse	PMID:7691848
Cellular Component	GO:0070062	extracellular exosome	CAP1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	CAP1	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	CAP1	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	CAP1	HDA		Human	PMID:23533145
Cellular Component	GO:0005925	focal adhesion	CAP1	HDA		Human	PMID:21423176
Biological Process	GO:0030036	actin cytoskeleton organization	Cap1	IMP		Mouse	PMID:15004221
Biological Process	GO:0001667	ameboidal-type cell migration	Cap1	IMP		Mouse	PMID:15004221
Biological Process	GO:0000902	cell morphogenesis	Cap1	IGI	SGD:S000005082	Mouse	PMID:7691848
Biological Process	GO:0008078	mesodermal cell migration	cap1	IMP		Zfish	PMID:15380064
Biological Process	GO:0006898	receptor-mediated endocytosis	Cap1	IMP		Mouse	PMID:15004221
Biological Process	GO:0001756	somitogenesis	cap1	IMP	ZFIN:ZDB-MRPHLNO-041213-1	Zfish	PMID:17689522

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern