Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CALHM1
  • Mouse genes Calhm1
  • Rat genes Calhm1
  • Zfish genes calhm1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Calhm1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005227	calcium activated cation channel activity	CALHM1	IDA		Human	PMID:22711817
Molecular Function	GO:0042802	identical protein binding	CALHM1	IPI	UniProtKB:Q8IU99	Human	PMID:18585350
Molecular Function	GO:0005515	protein binding	CALHM1	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CALHM1	IPI	UniProtKB:P48730-2	Human	PMID:32814053
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Calhm1	IDA		Mouse	MGI:MGI:5432299|PMID:22711817
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	CALHM1	IDA		Human	PMID:22711817
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	CALHM1	IDA		Human	PMID:23300080
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	Calhm1	IMP		Mouse	MGI:MGI:5475054|PMID:23467090
Cellular Component	GO:0016323	basolateral plasma membrane	Calhm1	IDA		Mouse	MGI:MGI:6407472|PMID:30804437
Cellular Component	GO:0005886	plasma membrane	CALHM1	IDA		Human	PMID:22711817
Cellular Component	GO:0005886	plasma membrane	CALHM1	IDA		Human	PMID:23300080
Biological Process	GO:0015867	ATP transport	Calhm1	IMP		Mouse	MGI:MGI:5475054|PMID:23467090
Biological Process	GO:0006812	monoatomic cation transport	CALHM1	IDA		Human	PMID:22711817
Biological Process	GO:0051291	protein heterooligomerization	Calhm1	IDA		Mouse	MGI:MGI:6269080|PMID:29681531
Biological Process	GO:0051260	protein homooligomerization	CALHM1	IDA		Human	PMID:23300080
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	CALHM1	IDA		Human	PMID:23300080
Biological Process	GO:0050913	sensory perception of bitter taste	Calhm1	IMP		Mouse	MGI:MGI:5475054|PMID:23467090
Biological Process	GO:0050916	sensory perception of sweet taste	Calhm1	IMP		Mouse	MGI:MGI:5475054|PMID:23467090
Biological Process	GO:0050909	sensory perception of taste	Calhm1	IMP		Mouse	MGI:MGI:5475054|PMID:23467090
Biological Process	GO:0050917	sensory perception of umami taste	Calhm1	IMP		Mouse	MGI:MGI:5475054|PMID:23467090

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern