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Calhm1 Gene Detail
Summary
  • Symbol
    Calhm1
  • Name
    calcium homeostasis modulator 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:3643383
    NCBI Gene: 546729
  • Gene Overview
    MyGene.info: CALHM1
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr19:47141035-47144174 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 39.36 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    73 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3643383
protein coding gene Chr19:47141035-47144174 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025225
protein coding gene Chr19:46918516-46921702 (-)
A/J MGP_AJ_G0025201
protein coding gene Chr19:44577026-44580145 (-)
AKR/J MGP_AKRJ_G0025170
protein coding gene Chr19:46035701-46038857 (-)
BALB/cJ MGP_BALBcJ_G0025196
protein coding gene Chr19:44634519-44637590 (-)
C3H/HeJ MGP_C3HHeJ_G0024956
protein coding gene Chr19:46213671-46216832 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025639
protein coding gene Chr19:48039772-48042885 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023052
protein coding gene Chr19:43820068-43823129 (-)
CAST/EiJ MGP_CASTEiJ_G0024421
protein coding gene Chr19:46027598-46030686 (-)
CBA/J MGP_CBAJ_G0024936
protein coding gene Chr19:50477505-50480673 (-)
DBA/2J MGP_DBA2J_G0025068
protein coding gene Chr19:44392360-44395472 (-)
FVB/NJ MGP_FVBNJ_G0025029
protein coding gene Chr19:44182363-44185491 (-)
LP/J MGP_LPJ_G0025154
protein coding gene Chr19:46813730-46818466 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025060
protein coding gene Chr19:49764344-49769969 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025697
protein coding gene Chr19:46153482-46156611 (-)
PWK/PhJ MGP_PWKPhJ_G0024170
protein coding gene Chr19:44355374-44358541 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023973
protein coding gene Chr19:44813687-44816795 (-)
WSB/EiJ MGP_WSBEiJ_G0024491
protein coding gene Chr19:46300748-46303902 (-)



Homology
more
  • Human Ortholog
    CALHM1, calcium homeostasis modulator 1
  • Vertebrate Orthologs
    12
  • Human Ortholog
    CALHM1, calcium homeostasis modulator 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FAM26C
  • Links
    NCBI Gene ID: 255022
    neXtProt AC: NX_Q8IU99
    UniProt: Q8IU99

  • Chr Location
    10q24.33; chr10:103453387-103458891 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 55508
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;2 zebrafish;2 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CALHM1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit altered cortical neuron electrical properties.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 546729 NCBI Gene Model | MGI Sequence Detail 3140 C57BL/6J ±  kb
transcript NM_001081271 RefSeq | MGI Sequence Detail 1047 Not Specified  
polypeptide D3Z291 UniProt | EBI | MGI Sequence Detail 348 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 2
    Primer pair 1
    Other 1

    Microarray probesets 1
References
more
  • Summaries
    All 24
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 12
  • Earliest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62
  • Latest
    J:264580 Sclafani A, et al., Greater reductions in fat preferences in CALHM1 than CD36 knockout mice. Am J Physiol Regul Integr Comp Physiol. 2018 Sep 1;315(3):R576-R585

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory