Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CACNG3
  • Mouse genes Cacng3
  • Rat genes Cacng3
  • Zfish genes cacng3a,cacng3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cacng3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	Cacng3	IDA		Rat	PMID:12771129|RGD:13515082
Molecular Function	GO:0030165	PDZ domain binding	Cacng3	IDA		Rat	PMID:15001777|RGD:1304305
Molecular Function	GO:0005515	protein binding	Cacng3	IPI	UniProtKB:P23818|UniProtKB:Q9JKC7	Mouse	MGI:MGI:3794899|PMID:18341993
Cellular Component	GO:0032281	AMPA glutamate receptor complex	Cacng3	IDA		Mouse	PMID:22632720
Cellular Component	GO:0032281	AMPA glutamate receptor complex	Cacng3	IDA		Rat	PMID:19265014|RGD:8554136
Cellular Component	GO:0030425	dendrite	Cacng3	IDA		Rat	PMID:15001777|RGD:1304305
Cellular Component	GO:0060076	excitatory synapse	Cacng3	IDA		Rat	PMID:15001777|RGD:1304305
Cellular Component	GO:0098978	glutamatergic synapse	Cacng3	IDA		Mouse	PMID:18753375
Cellular Component	GO:0098978	glutamatergic synapse	Cacng3	IMP		Mouse	PMID:18753375
Cellular Component	GO:0098978	glutamatergic synapse	Cacng3	IDA		Rat	PMID:12771129|RGD:13515082
Cellular Component	GO:0098839	postsynaptic density membrane	Cacng3	IDA		Mouse	PMID:27076426
Cellular Component	GO:0098839	postsynaptic density membrane	Cacng3	IDA		Rat	PMID:12771129|RGD:13515082
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Cacng3	IDA		Mouse	PMID:27076426
Cellular Component	GO:0036477	somatodendritic compartment	Cacng3	IDA		Mouse	MGI:MGI:3794899|PMID:18341993
Biological Process	GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	Cacng3	IDA		Mouse	PMID:18753375
Biological Process	GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	Cacng3	IMP		Mouse	PMID:18753375
Biological Process	GO:2000969	positive regulation of AMPA receptor activity	Cacng3	IDA		Rat	PMID:12771129|RGD:13515082
Biological Process	GO:0008104	protein localization	Cacng3	IMP		Mouse	MGI:MGI:3794899|PMID:18341993
Biological Process	GO:0006605	protein targeting	Cacng3	IMP		Mouse	MGI:MGI:3794899|PMID:18341993
Biological Process	GO:2000311	regulation of AMPA receptor activity	Cacng3	IDA		Rat	PMID:17880894|RGD:8553817
Biological Process	GO:2000311	regulation of AMPA receptor activity	Cacng3	IDA		Rat	PMID:19234459|RGD:8554069

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern