Cacng3
Gene Detail

Symbol Name ID

Cacng3 calcium channel, voltage-dependent, gamma subunit 3 MGI:1859165

Feature Type

protein coding gene

Genetic Map

Chromosome 7

66.81 cM, cytoband F3
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr7:122671744-122769391 bp, + strand From Ensembl annotation of GRCm38   97648 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Mammalian homology

human; rat; cattle; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human Cacng3 ± 2 cM)

Gene Tree: Cacng3

Human ortholog

CACNG3 calcium channel, voltage-dependent, gamma subunit 3 NCBI Gene ID 10368
Human Chr16:24266876-24373737 bp, + strand Reference GRCh37.p2 Primary Assembly

Alleles and phenotypes

All alleles(2) : Targeted(2)
 

Male mice homozygous for disruptions in this gene have elevated cholesterol and HDL levels.

 

Gene Ontology (GO) classifications

All GO classifications: (15 annotations)

Process	calcium ion transmembrane transport, calcium ion transport, ...
Component	alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, integral to membrane, ...
Function	calcium channel activity, ion channel activity, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (124)    Tissues (78)    Images (29)
Theiler Stages: 17, 19, 20, 22, 23, 28

Assay Type	Results
RNA in situ	43
In situ reporter (knock in)	36
RT-PCR	45

cDNA source data(5)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(7) cDNA(5) Primer pair(2)
Microarray probesets(2)

Other database links

Ensembl Gene Model	ENSMUSG00000066189 (Evidence)
Entrez Gene	54376 (Evidence)
UniGene	444212
DFCI	TC1647164, TC1709444
DoTS	DT.55157802, DT.91331113
NIA Mouse Gene Index	U063686
Consensus CDS Project	CCDS21816.1
International Mouse Knockout Project Status	Cacng3

Sequences

Length	Strain/Species
genomic	ENSMUSG00000066189	Ensembl Gene Model | MGI Sequence Detail	97648	C57BL/6J
transcript	ENSMUST00000084615	Ensembl | MGI Sequence Detail	1523	Not Applicable
polypeptide	ENSMUSP00000081664	Ensembl | MGI Sequence Detail	315	Not Applicable

All sequences(16) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(479 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR004031	PMP-22/EMP/MP20/Claudin
InterPro	IPR008368	Voltage-dependent calcium channel, gamma subunit
Protein Ontology	PR:000004952	voltage-dependent calcium channel gamma-3 subunit

References

(Earliest) J:61749 Burgess DL, et al., Identification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplication. Genome Res. 1999 Dec;9(12):1204-13
(Latest) J:188364 Schwenk J, et al., High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes. Neuron. 2012 May 24;74(4):621-33
All references(27)