Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Cacnb1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CACNB1
- Mouse genes Cacnb1
- Rat genes Cacnb1
- Zfish genes cacnb1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cacnb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	Cacnb1	IGI	MGI:MGI:109482	Mouse	PMID:11756409
Molecular Function	GO:0042802	identical protein binding	Cacnb1	IPI	UniProtKB:P54283	Rat	PMID:18776052\|RGD:13432277
Molecular Function	GO:0051219	phosphoprotein binding	Cacnb1	IPI	RGD:10284	Rat	PMID:19840220\|RGD:7207260
Molecular Function	GO:0005515	protein binding	CACNB1	IPI	UniProtKB:P55040	Human	PMID:17052716
Molecular Function	GO:0005515	protein binding	CACNB1	IPI	UniProtKB:P56545-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CACNB1	IPI	UniProtKB:P55040	Human	PMID:35122502
Molecular Function	GO:0005515	protein binding	Cacnb1	IPI	PR:O55017	Mouse	PMID:10328888
Molecular Function	GO:0005515	protein binding	Cacnb1	IPI	PR:P97445	Mouse	PMID:10328888
Molecular Function	GO:0005515	protein binding	Cacnb1	IPI	PR:P97445	Mouse	PMID:1370480
Molecular Function	GO:0005515	protein binding	Cacnb1	IPI	UniProtKB:Q05152	Rat	PMID:16049174\|RGD:8553837
Molecular Function	GO:0005515	protein binding	Cacnb1	IPI	UniProtKB:Q66L44	Rat	PMID:24751537\|RGD:10047103
Molecular Function	GO:0005515	protein binding	cacnb1	IPI	ZFIN:ZDB-GENE-040801-248	Zfish	PMID:23736855
Molecular Function	GO:0019904	protein domain specific binding	Cacnb1	IPI	RGD:10284	Rat	PMID:19840220\|RGD:7207260
Molecular Function	GO:0019901	protein kinase binding	Cacnb1	IDA		Rat	PMID:18205403\|RGD:7175532
Molecular Function	GO:0019901	protein kinase binding	Cacnb1	IPI	RGD:10284	Rat	PMID:19840220\|RGD:7207260
Molecular Function	GO:0005245	voltage-gated calcium channel activity	CACNB1	IGI	UniProtKB:O00555,UniProtKB:P54289	Human	PMID:21883149
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Cacnb1	IDA		Mouse	PMID:1370480
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Cacnb1	IMP	MGI:MGI:2181804	Mouse	PMID:9929471
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Cacnb1	IMP	MGI:MGI:2181804	Mouse	PMID:8943043
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Cacnb1	IDA		Rat	PMID:16049183\|RGD:1582495
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Cacnb1	IDA		Rat	PMID:16554304\|RGD:1582591
Molecular Function	GO:0005245	voltage-gated calcium channel activity	cacnb1	IMP	ZFIN:ZDB-GENO-980202-506	Zfish	PMID:16286639
Molecular Function	GO:0005245	voltage-gated calcium channel activity	cacnb1	IMP	ZFIN:ZDB-GENO-980202-506	Zfish	PMID:19008220
Cellular Component	GO:0098978	glutamatergic synapse	Cacnb1	IDA		Rat	PMID:19996312\|RGD:13702458
Cellular Component	GO:0098978	glutamatergic synapse	Cacnb1	IMP		Rat	PMID:19996312\|RGD:13702458
Cellular Component	GO:0098794	postsynapse	Cacnb1	IDA		Rat	PMID:19996312\|RGD:13702458
Cellular Component	GO:0098794	postsynapse	Cacnb1	IMP		Rat	PMID:19996312\|RGD:13702458
Cellular Component	GO:0098793	presynapse	Cacnb1	IDA		Mouse	PMID:19996312
Cellular Component	GO:0098793	presynapse	Cacnb1	IMP		Mouse	PMID:19996312
Cellular Component	GO:0016529	sarcoplasmic reticulum	Cacnb1	IDA		Mouse	PMID:8943043
Cellular Component	GO:0030315	T-tubule	Cacnb1	IDA		Mouse	PMID:8943043
Cellular Component	GO:0005891	voltage-gated calcium channel complex	Cacnb1	IDA		Mouse	PMID:10328888
Cellular Component	GO:0005891	voltage-gated calcium channel complex	Cacnb1	IDA		Rat	PMID:16049183\|RGD:1582495
Cellular Component	GO:0005891	voltage-gated calcium channel complex	Cacnb1	IDA		Rat	PMID:16554304\|RGD:1582591
Cellular Component	GO:0005891	voltage-gated calcium channel complex	Cacnb1	IDA		Rat	PMID:19840220\|RGD:7207260
Cellular Component	GO:0005891	voltage-gated calcium channel complex	cacnb1	IDA		Zfish	PMID:19008220
Biological Process	GO:0006816	calcium ion transport	Cacnb1	IMP	MGI:MGI:2181804	Mouse	PMID:9929471
Biological Process	GO:0006816	calcium ion transport	Cacnb1	IMP	MGI:MGI:2181804	Mouse	PMID:8943043
Biological Process	GO:1904646	cellular response to amyloid-beta	CACNB1	IGI	UniProtKB:O00555,UniProtKB:P54289	Human	PMID:21883149
Biological Process	GO:0006936	muscle contraction	cacnb1	IMP	ZFIN:ZDB-GENO-060313-1	Zfish	PMID:16368137
Biological Process	GO:0006612	protein targeting to membrane	Cacnb1	IMP	MGI:MGI:2181804	Mouse	PMID:8943043
Biological Process	GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	CACNB1	IGI	UniProtKB:O00555,UniProtKB:P05067:PRO_0000000092,UniProtKB:P54289	Human	PMID:21883149
Biological Process	GO:0070978	voltage-gated calcium channel complex assembly	cacnb1	IMP	ZFIN:ZDB-GENO-980202-506	Zfish	PMID:19008220

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/09/2025 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.