Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BMP5
  • Mouse genes Bmp5
  • Rat genes Bmp5
  • Zfish genes bmp5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bmp5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070700	BMP receptor binding	BMP5	IDA		Human	PMID:7811286
Molecular Function	GO:0005515	protein binding	BMP5	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Bmp5	IPI	PR:Q8VEA6	Mouse	PMID:14660436
Cellular Component	GO:0005615	extracellular space	Bmp5	IDA		Rat	PMID:18758911|RGD:2301841
Cellular Component	GO:0031982	vesicle	Bmp5	IDA		Rat	PMID:18758911|RGD:2301841
Biological Process	GO:1905069	allantois development	Bmp5	IGI	UniProtKB:P23359	Mouse	MGI:MGI:1332253|PMID:10079236
Biological Process	GO:0097065	anterior head development	Bmp5	IMP	MGI:MGI:2679550	Mouse	PMID:26234751
Biological Process	GO:0048738	cardiac muscle tissue development	Bmp5	IGI	UniProtKB:P23359	Mouse	MGI:MGI:1332253|PMID:10079236
Biological Process	GO:0060411	cardiac septum morphogenesis	Bmp5	IGI	UniProtKB:P23359	Mouse	MGI:MGI:1332253|PMID:10079236
Biological Process	GO:0060710	chorio-allantoic fusion	Bmp5	IGI	UniProtKB:P23359	Mouse	MGI:MGI:1332253|PMID:10079236
Biological Process	GO:0043583	ear development	Bmp5	IMP	MGI:MGI:3521993	Mouse	PMID:26234751
Biological Process	GO:0043583	ear development	Bmp5	IMP	MGI:MGI:2679550	Mouse	PMID:26234751
Biological Process	GO:0043583	ear development	Bmp5	IMP	MGI:MGI:3510601	Mouse	PMID:26234751
Biological Process	GO:0003272	endocardial cushion formation	Bmp5	IGI	UniProtKB:P23359	Mouse	MGI:MGI:1332253|PMID:10079236
Biological Process	GO:0061384	heart trabecula morphogenesis	Bmp5	IGI	UniProtKB:P23359	Mouse	MGI:MGI:1332253|PMID:10079236
Biological Process	GO:0030902	hindbrain development	Bmp5	IGI	UniProtKB:P23359	Mouse	MGI:MGI:1332253|PMID:10079236
Biological Process	GO:0030539	male genitalia development	Bmp5	IGI	MGI:MGI:88182	Mouse	PMID:9664685
Biological Process	GO:0032348	negative regulation of aldosterone biosynthetic process	BMP5	IDA		Human	PMID:19584291
Biological Process	GO:0008285	negative regulation of cell population proliferation	BMP5	IDA		Human	PMID:19584291
Biological Process	GO:2000065	negative regulation of cortisol biosynthetic process	BMP5	IDA		Human	PMID:19584291
Biological Process	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway	BMP5	IDA		Human	PMID:19584291
Biological Process	GO:0010894	negative regulation of steroid biosynthetic process	BMP5	IDA		Human	PMID:19584291
Biological Process	GO:0014032	neural crest cell development	bmp5	IMP	ZFIN:ZDB-MRPHLNO-050902-1	Zfish	PMID:27790787
Biological Process	GO:0021502	neural fold elevation formation	Bmp5	IGI	UniProtKB:P23359	Mouse	MGI:MGI:1332253|PMID:10079236
Biological Process	GO:0007389	pattern specification process	Bmp5	IMP	MGI:MGI:1858106	Mouse	PMID:1339316
Biological Process	GO:0007389	pattern specification process	Bmp5	IMP	MGI:MGI:2153906	Mouse	PMID:1339316
Biological Process	GO:0007389	pattern specification process	Bmp5	IMP	MGI:MGI:2153907	Mouse	PMID:1339316
Biological Process	GO:0007389	pattern specification process	Bmp5	IMP	MGI:MGI:1930367	Mouse	PMID:1339316
Biological Process	GO:0003344	pericardium morphogenesis	Bmp5	IGI	UniProtKB:P23359	Mouse	MGI:MGI:1332253|PMID:10079236
Biological Process	GO:0060037	pharyngeal system development	Bmp5	IGI	UniProtKB:P23359	Mouse	MGI:MGI:1332253|PMID:10079236
Biological Process	GO:0008284	positive regulation of cell population proliferation	BMP5	IDA		Human	PMID:15516325
Biological Process	GO:1900006	positive regulation of dendrite development	BMP5	IDA		Human	PMID:11580864
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	BMP5	IDA		Human	PMID:11865031
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	bmp5	IMP	ZFIN:ZDB-MRPHLNO-050902-1	Zfish	PMID:27790787
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	BMP5	IDA		Human	PMID:11580864
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	bmp5	IMP	ZFIN:ZDB-MRPHLNO-050902-1	Zfish	PMID:27790787
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	BMP5	IDA		Human	PMID:15516325
Biological Process	GO:0001501	skeletal system development	Bmp5	IMP	MGI:MGI:1858106	Mouse	PMID:1339316
Biological Process	GO:0001501	skeletal system development	Bmp5	IMP	MGI:MGI:2153907	Mouse	PMID:1339316
Biological Process	GO:0001501	skeletal system development	Bmp5	IMP	MGI:MGI:2153906	Mouse	PMID:1339316
Biological Process	GO:0001501	skeletal system development	Bmp5	IMP	MGI:MGI:1857400	Mouse	PMID:1339316
Biological Process	GO:0003323	type B pancreatic cell development	BMP5	IDA		Human	PMID:11865031

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern