Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BHMT
  • Mouse genes Bhmt
  • Rat genes Bhmt
  • Zfish genes bhmt
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bhmt

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047150	betaine-homocysteine S-methyltransferase activity	BHMT	IDA		Human	PMID:10529246
Molecular Function	GO:0047150	betaine-homocysteine S-methyltransferase activity	BHMT	IDA		Human	PMID:18230605
Molecular Function	GO:0047150	betaine-homocysteine S-methyltransferase activity	BHMT	IDA		Human	PMID:8798461
Molecular Function	GO:0047150	betaine-homocysteine S-methyltransferase activity	BHMT	IDA		Human	PMID:9681996
Molecular Function	GO:0047150	betaine-homocysteine S-methyltransferase activity	Bhmt	IDA		Mouse	PMID:15217352
Molecular Function	GO:0047150	betaine-homocysteine S-methyltransferase activity	Bhmt	IMP		Rat	PMID:12487625|RGD:724611
Molecular Function	GO:0047150	betaine-homocysteine S-methyltransferase activity	Bhmt	IDA		Rat	PMID:15845641|RGD:1359026
Molecular Function	GO:0047150	betaine-homocysteine S-methyltransferase activity	Bhmt	IDA		Rat	PMID:28288879|RGD:151356626
Molecular Function	GO:0042802	identical protein binding	Bhmt	IDA		Rat	PMID:28288879|RGD:151356626
Molecular Function	GO:0008168	methyltransferase activity	Bhmt	IDA		Rat	PMID:15845641|RGD:1359026
Molecular Function	GO:0044877	protein-containing complex binding	Bhmt	IDA		Rat	PMID:17669278|RGD:2303511
Molecular Function	GO:0008270	zinc ion binding	BHMT	IDA		Human	PMID:12220488
Molecular Function	GO:0008270	zinc ion binding	BHMT	IDA		Human	PMID:18230605
Cellular Component	GO:0005829	cytosol	Bhmt	IDA		Rat	PMID:19239903|RGD:7242903
Cellular Component	GO:0005829	cytosol	Bhmt	IDA		Rat	PMID:28288879|RGD:151356626
Cellular Component	GO:0070062	extracellular exosome	BHMT	IDA		Human	PMID:21082674
Cellular Component	GO:0070062	extracellular exosome	BHMT	HDA		Human	PMID:23533145
Cellular Component	GO:0005634	nucleus	Bhmt	IDA		Rat	PMID:28288879|RGD:151356626
Cellular Component	GO:0032991	protein-containing complex	Bhmt	IDA		Rat	PMID:17669278|RGD:2303511
Biological Process	GO:0071266	'de novo' L-methionine biosynthetic process	BHMT	IMP		Human	PMID:10529246
Biological Process	GO:0006577	amino-acid betaine metabolic process	BHMT	IDA		Human	PMID:18230605
Biological Process	GO:0055123	digestive system development	bhmt	IMP	ZFIN:ZDB-MRPHLNO-120111-6	Zfish	PMID:21952238
Biological Process	GO:0055123	digestive system development	bhmt	IMP	ZFIN:ZDB-MRPHLNO-120111-7	Zfish	PMID:21952238
Biological Process	GO:0055123	digestive system development	bhmt	IMP	ZFIN:ZDB-MRPHLNO-120111-5	Zfish	PMID:21952238
Biological Process	GO:0071267	L-methionine salvage	BHMT	IDA		Human	PMID:18230605
Biological Process	GO:0009086	methionine biosynthetic process	Bhmt	IDA		Mouse	PMID:15217352
Biological Process	GO:0009086	methionine biosynthetic process	Bhmt	IDA		Rat	PMID:15845641|RGD:1359026
Biological Process	GO:0006479	protein methylation	Bhmt	IDA		Rat	PMID:15845641|RGD:1359026
Biological Process	GO:0010243	response to organonitrogen compound	Bhmt	IEP		Rat	PMID:19239903|RGD:7242903
Biological Process	GO:0003323	type B pancreatic cell development	bhmt	IMP	ZFIN:ZDB-MRPHLNO-120111-5	Zfish	PMID:21952238

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern