Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BHLHE22
  • Mouse genes Bhlhe22
  • Rat genes Bhlhe22
  • Zfish genes bhlhe22
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bhlhe22

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Bhlhe22	IDA		Mouse	PMID:22284184
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Bhlhe22	IMP	MGI:MGI:4440742	Mouse	PMID:22284184
Molecular Function	GO:0042802	identical protein binding	Bhlhe22	IPI	PR:Q8C6A8	Mouse	PMID:22284184
Molecular Function	GO:0005515	protein binding	Bhlhe22	IPI	PR:Q8BZ97	Mouse	PMID:22284184
Molecular Function	GO:0005515	protein binding	bhlhe22	IPI	ZFIN:ZDB-GENE-041114-172	Zfish	PMID:30813944
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	BHLHE22	IDA		Human	PMID:28473536
Cellular Component	GO:0005634	nucleus	Bhlhe22	IDA		Mouse	PMID:22284184
Biological Process	GO:0035881	amacrine cell differentiation	Bhlhe22	IMP	MGI:MGI:3707409	Mouse	PMID:17092954
Biological Process	GO:0021960	anterior commissure morphogenesis	Bhlhe22	IMP	MGI:MGI:4440742	Mouse	PMID:22284184
Biological Process	GO:0021952	central nervous system projection neuron axonogenesis	Bhlhe22	IMP	MGI:MGI:4440742	Mouse	PMID:22284184
Biological Process	GO:0021952	central nervous system projection neuron axonogenesis	Bhlhe22	IMP	MGI:MGI:2684610,MGI:MGI:4440744	Mouse	PMID:22284184
Biological Process	GO:0021796	cerebral cortex regionalization	Bhlhe22	IMP	MGI:MGI:3707409	Mouse	PMID:23431145
Biological Process	GO:0021540	corpus callosum morphogenesis	Bhlhe22	IMP	MGI:MGI:4440742	Mouse	PMID:22284184
Biological Process	GO:0021540	corpus callosum morphogenesis	Bhlhe22	IMP	MGI:MGI:2684610,MGI:MGI:4440744	Mouse	PMID:22284184
Biological Process	GO:0021957	corticospinal tract morphogenesis	Bhlhe22	IMP	MGI:MGI:4440742	Mouse	PMID:22284184
Biological Process	GO:0021957	corticospinal tract morphogenesis	Bhlhe22	IMP	MGI:MGI:2684610,MGI:MGI:4440744	Mouse	PMID:22284184
Biological Process	GO:0021957	corticospinal tract morphogenesis	Bhlhe22	IGI	MGI:MGI:99217	Mouse	PMID:22284184
Biological Process	GO:0097154	GABAergic neuron differentiation	Bhlhe22	IMP	MGI:MGI:3707409	Mouse	PMID:17092954
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Bhlhe22	IDA		Mouse	PMID:12213201
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Bhlhe22	IMP	MGI:MGI:4440742	Mouse	PMID:22284184
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	Bhlhe22	IMP	MGI:MGI:3707409	Mouse	PMID:17092954
Biological Process	GO:0060040	retinal bipolar neuron differentiation	Bhlhe22	IMP	MGI:MGI:3707409	Mouse	PMID:17092954

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern