Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BCL2L11
  • Mouse genes Bcl2l11
  • Rat genes Bcl2l11
  • Zfish genes bcl2l11
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bcl2l11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008017	microtubule binding	Bcl2l11	IDA		Mouse	PMID:16832056
Molecular Function	GO:0060090	molecular adaptor activity	Bcl2l11	IDA		Mouse	MGI:MGI:3775548|PMID:16645638
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07817-1	Human	PMID:14596824
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:P10415	Human	PMID:15694340
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:P97287	Human	PMID:15694340
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07440	Human	PMID:15694340
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07817-1	Human	PMID:15694340
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q92843	Human	PMID:15694340
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:P10415	Human	PMID:16697956
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07817	Human	PMID:16697956
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07820	Human	PMID:16697956
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q16548	Human	PMID:16697956
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q92843	Human	PMID:16697956
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:P10415	Human	PMID:17074758
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:P68451	Human	PMID:17074758
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:P10415	Human	PMID:17289999
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:P97287	Human	PMID:17289999
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07440	Human	PMID:17289999
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07812	Human	PMID:17289999
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07817-1	Human	PMID:17289999
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q92843	Human	PMID:17289999
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07812	Human	PMID:17525735
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07817	Human	PMID:17525735
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07820	Human	PMID:17525735
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:P63244	Human	PMID:18420585
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:P68451	Human	PMID:18551131
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07812	Human	PMID:18948948
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07812	Human	PMID:19427863
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q92934	Human	PMID:19427863
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07820	Human	PMID:20085765
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:P97287	Human	PMID:20627101
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07820	Human	PMID:21132008
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:P10415	Human	PMID:21199865
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07812	Human	PMID:21199865
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07817-1	Human	PMID:21199865
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07820	Human	PMID:21199865
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q92843	Human	PMID:21199865
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07820	Human	PMID:21507240
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07817-1	Human	PMID:21671007
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q9HD36	Human	PMID:22498477
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07817-1	Human	PMID:22516262
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07820	Human	PMID:22516262
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07812	Human	PMID:23235460
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q9HD36	Human	PMID:23235460
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07817-1	Human	PMID:23245996
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07820	Human	PMID:23245996
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07812	Human	PMID:23374347
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q9HD36	Human	PMID:23563182
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:P10415	Human	PMID:23845444
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:P03495	Human	PMID:24008843
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:P43364-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07813-1	Human	PMID:25497728
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:P10415	Human	PMID:26004684
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07820	Human	PMID:26859456
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:P40855	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q07817	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q13064	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q16548	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q86UW9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q8N6Y0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q92843	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q9HD36	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BCL2L11	IPI	UniProtKB:P07237	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Bcl2l11	IPI	UniProtKB:Q07817-1	Mouse	MGI:MGI:3712679|PMID:17177603
Molecular Function	GO:0005515	protein binding	Bcl2l11	IPI	UniProtKB:D3ZQG6|UniProtKB:P63102|UniProtKB:P63170|UniProtKB:Q9ESN6	Mouse	MGI:MGI:5294518|PMID:21478148
Molecular Function	GO:0005515	protein binding	Bcl2l11	IPI	UniProtKB:P97287	Mouse	MGI:MGI:5315677|PMID:20921992
Molecular Function	GO:0005515	protein binding	Bcl2l11	IPI	UniProtKB:Q07817|UniProtKB:Q07820|UniProtKB:Q8CEG8	Mouse	MGI:MGI:5796064|PMID:27013495
Molecular Function	GO:0005515	protein binding	Bcl2l11	IPI	UniProtKB:P97287	Mouse	MGI:MGI:5315340|PMID:17289999
Molecular Function	GO:0005515	protein binding	Bcl2l11	IPI	UniProtKB:P03182	Mouse	MGI:MGI:6093015|PMID:19293378
Molecular Function	GO:0005515	protein binding	Bcl2l11	IPI	UniProtKB:P97287	Mouse	MGI:MGI:4939122|PMID:18589438
Molecular Function	GO:0005515	protein binding	Bcl2l11	IPI	UniProtKB:P10417|UniProtKB:Q9DBC7	Mouse	MGI:MGI:5508733|PMID:21151042
Molecular Function	GO:0005515	protein binding	Bcl2l11	IPI	UniProtKB:P97287	Mouse	MGI:MGI:5514334|PMID:16543145
Molecular Function	GO:0005515	protein binding	Bcl2l11	IPI	UniProtKB:P97287	Mouse	MGI:MGI:3689775|PMID:15694340
Molecular Function	GO:0005515	protein binding	Bcl2l11	IPI	UniProtKB:P63244	Mouse	MGI:MGI:3834293|PMID:18420585
Molecular Function	GO:0005515	protein binding	Bcl2l11	IPI	PR:P63168	Mouse	PMID:14561217
Molecular Function	GO:0005515	protein binding	Bcl2l11	IPI	PR:P63168	Mouse	PMID:15136728
Molecular Function	GO:0005515	protein binding	Bcl2l11	IPI	PR:P70345	Mouse	PMID:16645638
Molecular Function	GO:0005515	protein binding	Bcl2l11	IPI	RGD:620525	Rat	PMID:10579309|RGD:633263
Molecular Function	GO:0005515	protein binding	Bcl2l11	IPI	UniProtKB:Q9C040	Rat	PMID:21478148|RGD:8554586
Molecular Function	GO:0005515	protein binding	Bcl2l11	IPI	RGD:2200	Rat	PMID:9731710|RGD:704412
Molecular Function	GO:0019901	protein kinase binding	Bcl2l11	IPI	UniProtKB:Q2NL51|UniProtKB:Q9WV60	Mouse	MGI:MGI:4818524|PMID:20371704
Cellular Component	GO:0097136	Bcl-2 family protein complex	BCL2L11	IPI		Human	PMID:20066663
Cellular Component	GO:0097136	Bcl-2 family protein complex	Bcl2l11	IMP		Mouse	MGI:MGI:3775548|PMID:16645638
Cellular Component	GO:0005737	cytoplasm	Bcl2l11	IDA		Mouse	PMID:15136728
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Bcl2l11	IDA		Mouse	PMID:15136728
Cellular Component	GO:0016020	membrane	Bcl2l11	IDA		Mouse	PMID:15136728
Cellular Component	GO:0005739	mitochondrion	Bcl2l11	IDA		Mouse	PMID:15136728
Cellular Component	GO:0005739	mitochondrion	Bcl2l11	IDA		Rat	PMID:18058945|RGD:5128576
Biological Process	GO:1902263	apoptotic process involved in embryonic digit morphogenesis	Bcl2l11	IGI	MGI:MGI:99702	Mouse	PMID:15967824
Biological Process	GO:0001782	B cell homeostasis	Bcl2l11	IMP	MGI:MGI:3589204	Mouse	PMID:16055554
Biological Process	GO:0001782	B cell homeostasis	Bcl2l11	IGI	MGI:MGI:99702	Mouse	PMID:15967824
Biological Process	GO:0001782	B cell homeostasis	Bcl2l11	IMP	MGI:MGI:2156498	Mouse	PMID:16270031
Biological Process	GO:0001782	B cell homeostasis	Bcl2l11	IGI	MGI:MGI:1097161	Mouse	PMID:15967824
Biological Process	GO:0007420	brain development	Bcl2l11	IEP		Rat	PMID:18058945|RGD:5128576
Biological Process	GO:0007049	cell cycle	Bcl2l11	IMP	MGI:MGI:2156498	Mouse	PMID:17705137
Biological Process	GO:0007160	cell-matrix adhesion	Bcl2l11	IMP	MGI:MGI:2156483	Mouse	PMID:17276340
Biological Process	GO:1904646	cellular response to amyloid-beta	Bcl2l11	IEP		Rat	PMID:17287517|RGD:14394420
Biological Process	GO:0071392	cellular response to estradiol stimulus	Bcl2l11	IEP		Rat	PMID:17287517|RGD:14394420
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	Bcl2l11	IEP		Rat	PMID:12388545|RGD:704413
Biological Process	GO:0048066	developmental pigmentation	Bcl2l11	IGI	MGI:MGI:88138	Mouse	PMID:11709185
Biological Process	GO:0043583	ear development	Bcl2l11	IGI	MGI:MGI:88138	Mouse	PMID:11709185
Biological Process	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	Bcl2l11	IMP	MGI:MGI:2156498	Mouse	PMID:15967824
Biological Process	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	Bcl2l11	IGI	MGI:MGI:99702	Mouse	PMID:15967824
Biological Process	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	Bcl2l11	IGI	MGI:MGI:1097161	Mouse	PMID:15967824
Biological Process	GO:0001701	in utero embryonic development	Bcl2l11	IGI	MGI:MGI:97603	Mouse	PMID:16282979
Biological Process	GO:0019051	induction by virus of host apoptotic process	Bcl2l11	IDA		Mouse	PMID:15231831
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	BCL2L11	IDA		Human	PMID:11546872
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	Bcl2l11	IGI	MGI:MGI:99702	Mouse	PMID:15967824
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	Bcl2l11	IGI	MGI:MGI:1097161	Mouse	PMID:15967824
Biological Process	GO:0001822	kidney development	Bcl2l11	IGI	MGI:MGI:88138	Mouse	PMID:11709185
Biological Process	GO:0001776	leukocyte homeostasis	Bcl2l11	IGI	MGI:MGI:1097161	Mouse	PMID:15967824
Biological Process	GO:0001776	leukocyte homeostasis	Bcl2l11	IMP	MGI:MGI:2156498	Mouse	PMID:15967824
Biological Process	GO:0001776	leukocyte homeostasis	Bcl2l11	IGI	MGI:MGI:99702	Mouse	PMID:15967824
Biological Process	GO:0070227	lymphocyte apoptotic process	Bcl2l11	IMP	MGI:MGI:2156498	Mouse	PMID:16270031
Biological Process	GO:0002260	lymphocyte homeostasis	Bcl2l11	IGI	MGI:MGI:88138	Mouse	PMID:15818405
Biological Process	GO:0002260	lymphocyte homeostasis	Bcl2l11	IGI	MGI:MGI:88138	Mouse	PMID:11709185
Biological Process	GO:0002260	lymphocyte homeostasis	Bcl2l11	IMP	MGI:MGI:2156498	Mouse	PMID:11709185
Biological Process	GO:0008584	male gonad development	Bcl2l11	IGI	MGI:MGI:1206591	Mouse	PMID:16270031
Biological Process	GO:0030879	mammary gland development	Bcl2l11	IMP	MGI:MGI:2156483	Mouse	PMID:17276340
Biological Process	GO:0002262	myeloid cell homeostasis	Bcl2l11	IGI	MGI:MGI:99702	Mouse	PMID:15967824
Biological Process	GO:0002262	myeloid cell homeostasis	Bcl2l11	IGI	MGI:MGI:1097161	Mouse	PMID:15967824
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Bcl2l11	IGI	MGI:MGI:99702	Mouse	PMID:15967824
Biological Process	GO:0043065	positive regulation of apoptotic process	BCL2L11	IMP		Human	PMID:17289999
Biological Process	GO:0043065	positive regulation of apoptotic process	Bcl2l11	IMP	MGI:MGI:2156483	Mouse	PMID:17276340
Biological Process	GO:0043065	positive regulation of apoptotic process	Bcl2l11	IMP		Rat	PMID:12388545|RGD:704413
Biological Process	GO:0043065	positive regulation of apoptotic process	Bcl2l11	IMP		Rat	PMID:9731710|RGD:704412
Biological Process	GO:0034263	positive regulation of autophagy in response to ER overload	Bcl2l11	IMP		Rat	PMID:25772147|RGD:13782257
Biological Process	GO:0045787	positive regulation of cell cycle	Bcl2l11	IMP	MGI:MGI:2156498	Mouse	PMID:17705137
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Bcl2l11	IMP	MGI:MGI:2156498	Mouse	PMID:15967824
Biological Process	GO:2000271	positive regulation of fibroblast apoptotic process	BCL2L11	IDA		Human	PMID:11997495
Biological Process	GO:0070230	positive regulation of lymphocyte apoptotic process	Bcl2l11	IMP	MGI:MGI:2156498	Mouse	PMID:16270031
Biological Process	GO:1902110	positive regulation of mitochondrial membrane permeability involved in apoptotic process	Bcl2l11	IGI	MGI:MGI:99702	Mouse	PMID:15967824
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Bcl2l11	IDA		Mouse	PMID:15231831
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	BCL2L11	IMP		Human	PMID:19767770
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	BCL2L11	IDA		Human	PMID:21041309
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	BCL2L11	IMP		Human	PMID:17289999
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	BCL2L11	IGI	UniProtKB:P70444	Human	PMID:21041309
Biological Process	GO:0070234	positive regulation of T cell apoptotic process	Bcl2l11	IMP	MGI:MGI:2156498	Mouse	PMID:16832056
Biological Process	GO:0070234	positive regulation of T cell apoptotic process	Bcl2l11	IGI	MGI:MGI:88140	Mouse	PMID:16832056
Biological Process	GO:0048563	post-embryonic animal organ morphogenesis	Bcl2l11	IMP	MGI:MGI:2156483	Mouse	PMID:17276340
Biological Process	GO:0009791	post-embryonic development	Bcl2l11	IGI	MGI:MGI:88138	Mouse	PMID:11709185
Biological Process	GO:0042981	regulation of apoptotic process	BCL2L11	IDA		Human	PMID:18209102
Biological Process	GO:0042981	regulation of apoptotic process	Bcl2l11	IGI	MGI:MGI:88138	Mouse	PMID:15818405
Biological Process	GO:0048070	regulation of developmental pigmentation	Bcl2l11	IGI	MGI:MGI:88138	Mouse	PMID:15818405
Biological Process	GO:0046620	regulation of organ growth	Bcl2l11	IMP	MGI:MGI:2156483	Mouse	PMID:17276340
Biological Process	GO:0034976	response to endoplasmic reticulum stress	BCL2L11	IDA		Human	PMID:22761832
Biological Process	GO:0034976	response to endoplasmic reticulum stress	Bcl2l11	IDA		Mouse	MGI:MGI:4879048|PMID:21159964
Biological Process	GO:0007283	spermatogenesis	Bcl2l11	IGI	MGI:MGI:1206591	Mouse	PMID:16270031
Biological Process	GO:0048536	spleen development	Bcl2l11	IGI	MGI:MGI:88138	Mouse	PMID:15818405
Biological Process	GO:0070231	T cell apoptotic process	Bcl2l11	IGI	MGI:MGI:88140	Mouse	PMID:16832056
Biological Process	GO:0070231	T cell apoptotic process	Bcl2l11	IMP	MGI:MGI:2156498	Mouse	PMID:16832056
Biological Process	GO:0043029	T cell homeostasis	Bcl2l11	IGI	MGI:MGI:88138	Mouse	PMID:17591857
Biological Process	GO:0043029	T cell homeostasis	Bcl2l11	IMP	MGI:MGI:2156498	Mouse	PMID:16270031
Biological Process	GO:0070242	thymocyte apoptotic process	Bcl2l11	IGI	MGI:MGI:99702	Mouse	PMID:15967824
Biological Process	GO:0070242	thymocyte apoptotic process	Bcl2l11	IGI	MGI:MGI:1097161	Mouse	PMID:15967824
Biological Process	GO:0048538	thymus development	Bcl2l11	IGI	MGI:MGI:88138	Mouse	PMID:15818405
Biological Process	GO:0035148	tube formation	Bcl2l11	IMP	MGI:MGI:2156483	Mouse	PMID:17276340

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern