Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AURKC
  • Mouse genes Aurkc
  • Rat genes Aurkc
  • Zfish genes aurkb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aurkc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	AURKC	IPI	UniProtKB:O15392	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	AURKC	IPI	UniProtKB:O15392	Human	PMID:27332895
Molecular Function	GO:0005515	protein binding	AURKC	IPI	UniProtKB:Q9NQS7	Human	PMID:27332895
Molecular Function	GO:0005515	protein binding	AURKC	IPI	UniProtKB:A2RRN7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AURKC	IPI	UniProtKB:P32243-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AURKC	IPI	UniProtKB:Q96CA5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AURKC	IPI	UniProtKB:Q9NQS7	Human	PMID:32707033
Molecular Function	GO:0004672	protein kinase activity	AURKC	IDA		Human	PMID:15670791
Molecular Function	GO:0004672	protein kinase activity	Aurkc	IDA		Mouse	PMID:9809744
Cellular Component	GO:0005694	chromosome	Aurkc	IDA		Mouse	PMID:21558374
Cellular Component	GO:0000775	chromosome, centromeric region	Aurkc	IDA		Mouse	PMID:12584241
Cellular Component	GO:0000793	condensed chromosome	AURKC	IDA		Human	PMID:15670791
Cellular Component	GO:1990385	meiotic spindle midzone	Aurkc	IDA		Mouse	PMID:21558374
Cellular Component	GO:0030496	midbody	AURKC	IDA		Human	PMID:15670791
Cellular Component	GO:0051233	spindle midzone	AURKC	IDA		Human	PMID:15670791
Biological Process	GO:0007059	chromosome segregation	aurkb	IMP	ZFIN:ZDB-GENO-090720-1	Zfish	PMID:19543364
Biological Process	GO:0036089	cleavage furrow formation	aurkb	IMP	ZFIN:ZDB-GENO-090720-1	Zfish	PMID:19543364
Biological Process	GO:0000226	microtubule cytoskeleton organization	aurkb	IMP	ZFIN:ZDB-GENO-090720-1	Zfish	PMID:19543364
Biological Process	GO:0000281	mitotic cytokinesis	aurkb	IMP	ZFIN:ZDB-GENO-090720-1	Zfish	PMID:19543364
Biological Process	GO:0046777	protein autophosphorylation	Aurkc	IDA		Mouse	PMID:9809744
Biological Process	GO:0006468	protein phosphorylation	AURKC	IDA		Human	PMID:15670791

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern