Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Atp2b1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ATP2B1
- Mouse genes Atp2b1
- Rat genes Atp2b1
- Zfish genes atp2b1a,atp2b1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atp2b1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016887	ATP hydrolysis activity	ATP2B1	IDA		Human	PMID:30190470
Molecular Function	GO:0015085	calcium ion transmembrane transporter activity	ATP2B1	IDA		Human	PMID:18029012
Molecular Function	GO:0030165	PDZ domain binding	Atp2b1	IPI	RGD:628725	Rat	PMID:16554037\|RGD:1581788
Molecular Function	GO:0005515	protein binding	ATP2B1	IPI	UniProtKB:P62258	Human	PMID:18029012
Molecular Function	GO:0005515	protein binding	ATP2B1	IPI	UniProtKB:Q2M3R5	Human	PMID:22084111
Molecular Function	GO:0005515	protein binding	ATP2B1	IPI	UniProtKB:Q14160	Human	PMID:30126976
Molecular Function	GO:0005515	protein binding	ATP2B1	IPI	UniProtKB:Q9Y639	Human	PMID:30190470
Molecular Function	GO:0005515	protein binding	Atp2b1	IPI	UniProtKB:P48193	Mouse	MGI:MGI:5496297\|PMID:23460639
Molecular Function	GO:0005515	protein binding	Atp2b1	IPI	UniProtKB:P97300	Mouse	MGI:MGI:6114568\|PMID:28827723
Molecular Function	GO:0005515	protein binding	Atp2b1	IPI	PR:P70227	Mouse	PMID:16352659
Molecular Function	GO:0005515	protein binding	Atp2b1	IPI	PR:O55143	Mouse	PMID:16352659
Cellular Component	GO:0045177	apical part of cell	Atp2b1	IDA		Rat	PMID:18395836\|RGD:2317727
Cellular Component	GO:0016324	apical plasma membrane	Atp2b1	IDA		Rat	PMID:18395836\|RGD:2317727
Cellular Component	GO:0016323	basolateral plasma membrane	Atp2b1	IDA		Mouse	MGI:MGI:5496297\|PMID:23460639
Cellular Component	GO:0016323	basolateral plasma membrane	Atp2b1	IDA		Rat	PMID:16803870\|RGD:7205685
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	Atp2b1	IDA		Rat	PMID:20575074\|RGD:7205679
Cellular Component	GO:0032590	dendrite membrane	Atp2b1	IDA		Rat	PMID:20575074\|RGD:7205679
Cellular Component	GO:0032591	dendritic spine membrane	Atp2b1	IDA		Rat	PMID:20575074\|RGD:7205679
Cellular Component	GO:0070062	extracellular exosome	ATP2B1	HDA		Human	PMID:20458337
Cellular Component	GO:0098982	GABA-ergic synapse	Atp2b1	EXP		Rat	PMID:23622064\|RGD:13702180
Cellular Component	GO:0098982	GABA-ergic synapse	Atp2b1	IDA		Rat	PMID:23622064\|RGD:13702180
Cellular Component	GO:0098978	glutamatergic synapse	Atp2b1	IDA		Mouse	PMID:19233278
Cellular Component	GO:0098978	glutamatergic synapse	Atp2b1	EXP		Rat	PMID:23622064\|RGD:13702180
Cellular Component	GO:0098978	glutamatergic synapse	Atp2b1	IDA		Rat	PMID:23622064\|RGD:13702180
Cellular Component	GO:0001772	immunological synapse	Atp2b1	IDA		Mouse	MGI:MGI:6114568\|PMID:28827723
Cellular Component	GO:0016020	membrane	ATP2B1	HDA		Human	PMID:19946888
Cellular Component	GO:0045121	membrane raft	Atp2b1	IDA		Rat	PMID:17596212\|RGD:2317728
Cellular Component	GO:0032809	neuronal cell body membrane	Atp2b1	IDA		Rat	PMID:20575074\|RGD:7205679
Cellular Component	GO:0005654	nucleoplasm	ATP2B1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0098684	photoreceptor ribbon synapse	Atp2b1	IDA		Mouse	PMID:19233278
Cellular Component	GO:0005886	plasma membrane	ATP2B1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ATP2B1	IDA		Human	PMID:18029012
Cellular Component	GO:0048787	presynaptic active zone membrane	Atp2b1	EXP		Rat	PMID:23622064\|RGD:13702180
Cellular Component	GO:0048787	presynaptic active zone membrane	Atp2b1	IDA		Rat	PMID:23622064\|RGD:13702180
Cellular Component	GO:0042734	presynaptic membrane	Atp2b1	IDA		Mouse	MGI:MGI:6695685\|PMID:30862855
Cellular Component	GO:0042734	presynaptic membrane	Atp2b1	IDA		Mouse	PMID:19233278
Cellular Component	GO:0030672	synaptic vesicle membrane	Atp2b1	IDA		Mouse	MGI:MGI:6695685\|PMID:30862855
Biological Process	GO:0007568	aging	Atp2b1	IEP		Rat	PMID:7918552\|RGD:2317748
Biological Process	GO:0030282	bone mineralization	atp2b1a	IMP	ZFIN:ZDB-MRPHLNO-101206-1	Zfish	PMID:23353107
Biological Process	GO:0060349	bone morphogenesis	atp2b1a	IMP	ZFIN:ZDB-MRPHLNO-101206-1	Zfish	PMID:23353107
Biological Process	GO:0007420	brain development	Atp2b1	IEP		Rat	PMID:1328526\|RGD:2317749
Biological Process	GO:1901660	calcium ion export	Atp2b1	IMP		Rat	PMID:9227424\|RGD:2317732
Biological Process	GO:1990034	calcium ion export across plasma membrane	ATP2B1	IDA		Human	PMID:18029012
Biological Process	GO:0071386	cellular response to corticosterone stimulus	Atp2b1	IEP		Rat	PMID:10777776\|RGD:2317731
Biological Process	GO:0071305	cellular response to vitamin D	Atp2b1	IEP		Rat	PMID:11277270\|RGD:2317730
Biological Process	GO:0060119	inner ear receptor cell development	atp2b1a	IMP	ZFIN:ZDB-MRPHLNO-100414-3	Zfish	PMID:19218514
Biological Process	GO:0006874	intracellular calcium ion homeostasis	Atp2b1	IMP		Mouse	MGI:MGI:6114568\|PMID:28827723
Biological Process	GO:0006874	intracellular calcium ion homeostasis	Atp2b1	IMP		Mouse	MGI:MGI:3703409\|PMID:16956963
Biological Process	GO:0001818	negative regulation of cytokine production	Atp2b1	IMP		Mouse	MGI:MGI:6114568\|PMID:28827723
Biological Process	GO:0051481	negative regulation of cytosolic calcium ion concentration	ATP2B1	IMP		Human	PMID:29104511
Biological Process	GO:0051481	negative regulation of cytosolic calcium ion concentration	Atp2b1	IMP		Mouse	MGI:MGI:5689962\|PMID:22311909
Biological Process	GO:0003407	neural retina development	Atp2b1	IEP		Rat	PMID:16079002\|RGD:2317729
Biological Process	GO:0048840	otolith development	atp2b1a	IMP	ZFIN:ZDB-MRPHLNO-100414-3	Zfish	PMID:19218514
Biological Process	GO:0030501	positive regulation of bone mineralization	Atp2b1	IMP		Mouse	MGI:MGI:5780494\|PMID:26392310
Biological Process	GO:0051928	positive regulation of calcium ion transport	Atp2b1	IMP		Mouse	MGI:MGI:5780494\|PMID:26392310
Biological Process	GO:0048919	posterior lateral line neuromast development	atp2b1a	IMP	ZFIN:ZDB-MRPHLNO-100414-3	Zfish	PMID:19218514
Biological Process	GO:0048919	posterior lateral line neuromast development	atp2b1a	IMP	ZFIN:ZDB-MRPHLNO-101206-1	Zfish	PMID:21084119
Biological Process	GO:0008217	regulation of blood pressure	Atp2b1	IMP		Mouse	MGI:MGI:5689962\|PMID:22311909
Biological Process	GO:0008217	regulation of blood pressure	Atp2b1	IMP		Mouse	MGI:MGI:6282934\|PMID:24805951
Biological Process	GO:1900076	regulation of cellular response to insulin stimulus	ATP2B1	IMP		Human	PMID:29104511
Biological Process	GO:0051480	regulation of cytosolic calcium ion concentration	ATP2B1	IDA		Human	PMID:18029012
Biological Process	GO:0051480	regulation of cytosolic calcium ion concentration	Atp2b1	IMP		Mouse	MGI:MGI:6114568\|PMID:28827723
Biological Process	GO:0051480	regulation of cytosolic calcium ion concentration	Atp2b1	IMP		Mouse	MGI:MGI:6282934\|PMID:24805951
Biological Process	GO:0051480	regulation of cytosolic calcium ion concentration	Atp2b1	IMP		Mouse	MGI:MGI:6282970\|PMID:29950683
Biological Process	GO:0003056	regulation of vascular associated smooth muscle contraction	Atp2b1	IMP		Mouse	MGI:MGI:6282934\|PMID:24805951
Biological Process	GO:0009409	response to cold	Atp2b1	IEP		Rat	PMID:10777776\|RGD:2317731
Biological Process	GO:0007605	sensory perception of sound	atp2b1a	IMP	ZFIN:ZDB-MRPHLNO-101206-1	Zfish	PMID:21084119
Biological Process	GO:0034505	tooth mineralization	atp2b1a	IMP	ZFIN:ZDB-MRPHLNO-101206-1	Zfish	PMID:23353107

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.