Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATG4A
  • Mouse genes Atg4a
  • Rat genes Atg4a
  • Zfish genes atg4a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atg4a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019786	Atg8-specific peptidase activity	ATG4A	IDA		Human	PMID:31315929
Molecular Function	GO:0008234	cysteine-type peptidase activity	ATG4A	IDA		Human	PMID:12473658
Molecular Function	GO:0008234	cysteine-type peptidase activity	ATG4A	IDA		Human	PMID:15169837
Molecular Function	GO:0008234	cysteine-type peptidase activity	ATG4A	IDA		Human	PMID:21177865
Molecular Function	GO:0008234	cysteine-type peptidase activity	ATG4A	IDA		Human	PMID:30661429
Molecular Function	GO:0008234	cysteine-type peptidase activity	ATG4A	IDA		Human	PMID:32732290
Molecular Function	GO:0005515	protein binding	ATG4A	IPI	UniProtKB:Q8IVW4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ATG4A	IPI	UniProtKB:Q9H0R8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ATG4A	IPI	UniProtKB:Q9H0R8	Human	PMID:32296183
Biological Process	GO:0006914	autophagy	ATG4A	IDA		Human	PMID:30661429
Biological Process	GO:0051697	protein delipidation	ATG4A	IDA		Human	PMID:29458288
Biological Process	GO:0051697	protein delipidation	ATG4A	IDA		Human	PMID:32732290
Biological Process	GO:0006508	proteolysis	ATG4A	IDA		Human	PMID:12473658
Biological Process	GO:0006508	proteolysis	ATG4A	IDA		Human	PMID:15169837
Biological Process	GO:0006508	proteolysis	ATG4A	IDA		Human	PMID:21177865

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern