Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ATG14
  • Mouse genes Atg14
  • Rat genes Atg14
  • Zfish genes atg14
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Atg14

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051020	GTPase binding	ATG14	IPI	UniProtKB:A1A4Y4	Human	PMID:25891078
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q14457	Human	PMID:19050071
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q8NEB9	Human	PMID:19050071
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q14457	Human	PMID:19270696
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q8NEB9	Human	PMID:19270696
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q99570	Human	PMID:19270696
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q14457	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q8NEB9	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q14457	Human	PMID:21062745
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q14457	Human	PMID:22081109
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q14457	Human	PMID:22493499
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q8NEB9	Human	PMID:22493499
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q14457	Human	PMID:23112296
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q14457	Human	PMID:23332761
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q8NEB9	Human	PMID:23332761
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:A8MW95	Human	PMID:23954414
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q14457	Human	PMID:23954414
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q14457	Human	PMID:24034250
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q8NEB9	Human	PMID:24785657
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q9C035	Human	PMID:25127057
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q14457	Human	PMID:25490155
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q8NEB9	Human	PMID:25490155
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q14457	Human	PMID:25594178
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:P56962	Human	PMID:25686604
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q14457	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q14457	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q8NEB9	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q14457	Human	PMID:31806350
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q8NEB9	Human	PMID:31806350
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:A1L4K1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q14457	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q9NYP9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ATG14	IPI	UniProtKB:Q8NEB9	Human	PMID:33422265
Molecular Function	GO:0005515	protein binding	Atg14	IPI	UniProtKB:Q8VCQ3	Mouse	MGI:MGI:5634877|PMID:24849286
Molecular Function	GO:0005515	protein binding	Atg14	IPI	UniProtKB:P23242	Mouse	MGI:MGI:5915435|PMID:24705551
Molecular Function	GO:0005515	protein binding	Atg14	IPI	PR:Q9Z266	Mouse	PMID:22797916
Molecular Function	GO:0005515	protein binding	Atg14	IPI	PR:O88597	Mouse	PMID:27994061
Cellular Component	GO:0005776	autophagosome	ATG14	IDA		Human	PMID:19270696
Cellular Component	GO:0005776	autophagosome	ATG14	IDA		Human	PMID:25686604
Cellular Component	GO:0005930	axoneme	Atg14	IDA		Mouse	MGI:MGI:5527012|PMID:24089209
Cellular Component	GO:0097629	extrinsic component of omegasome membrane	ATG14	IDA		Human	PMID:21518905
Cellular Component	GO:0097632	extrinsic component of phagophore assembly site membrane	ATG14	IDA		Human	PMID:21518905
Cellular Component	GO:0044233	mitochondria-associated endoplasmic reticulum membrane	Atg14	IDA		Mouse	PMID:23455425
Cellular Component	GO:0045335	phagocytic vesicle	Atg14	IDA		Mouse	PMID:22493499
Cellular Component	GO:0034045	phagophore assembly site membrane	ATG14	IDA		Human	PMID:19270696
Cellular Component	GO:0035032	phosphatidylinositol 3-kinase complex, class III	ATG14	IPI		Human	PMID:25490155
Cellular Component	GO:0035032	phosphatidylinositol 3-kinase complex, class III	Atg14	IDA		Mouse	MGI:MGI:5619439|PMID:23332761
Biological Process	GO:0000045	autophagosome assembly	ATG14	IMP		Human	PMID:19270696
Biological Process	GO:0097352	autophagosome maturation	ATG14	IDA		Human	PMID:10625637
Biological Process	GO:0016240	autophagosome membrane docking	ATG14	IDA		Human	PMID:25686604
Biological Process	GO:0006914	autophagy	Atg14	IMP		Mouse	MGI:MGI:5619471|PMID:19270693
Biological Process	GO:0006914	autophagy	Atg14	IMP		Mouse	MGI:MGI:4438180|PMID:19270696
Biological Process	GO:0042149	cellular response to glucose starvation	Atg14	IDA		Mouse	MGI:MGI:5619439|PMID:23332761
Biological Process	GO:0009267	cellular response to starvation	ATG14	IMP		Human	PMID:23878393
Biological Process	GO:0045022	early endosome to late endosome transport	ATG14	IDA		Human	PMID:14617358
Biological Process	GO:0008333	endosome to lysosome transport	ATG14	IGI	UniProtKB:O95295	Human	PMID:22797916
Biological Process	GO:0016236	macroautophagy	ATG14	IMP		Human	PMID:23878393
Biological Process	GO:0000423	mitophagy	ATG14	IMP		Human	PMID:23878393
Biological Process	GO:0001933	negative regulation of protein phosphorylation	Atg14	IDA		Mouse	MGI:MGI:5619439|PMID:23332761
Biological Process	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	ATG14	IDA		Human	PMID:8999962
Biological Process	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	ATG14	IDA		Human	PMID:21062745
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Atg14	IDA		Mouse	MGI:MGI:5619439|PMID:23332761
Biological Process	GO:0010608	post-transcriptional regulation of gene expression	ATG14	IMP		Human	PMID:23878393
Biological Process	GO:0006468	protein phosphorylation	ATG14	IDA		Human	PMID:8999962
Biological Process	GO:0016241	regulation of macroautophagy	ATG14	IDA		Human	PMID:10625637
Biological Process	GO:0001932	regulation of protein phosphorylation	ATG14	IMP	UniProtKB:Q14457	Human	PMID:23878393
Biological Process	GO:0090207	regulation of triglyceride metabolic process	Atg14	IMP		Mouse	PMID:22992773
Biological Process	GO:0098780	response to mitochondrial depolarisation	ATG14	IMP		Human	PMID:23878393

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern