Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARRDC3
  • Mouse genes Arrdc3
  • Rat genes Arrdc3
  • Zfish genes arrdc3a,arrdc3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arrdc3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031699	beta-3 adrenergic receptor binding	ARRDC3	IDA		Human	PMID:21982743
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:P16144	Human	PMID:20603614
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:P07550	Human	PMID:23208550
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:P46934	Human	PMID:23208550
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:O00308	Human	PMID:23236378
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:P07550	Human	PMID:23236378
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:P46934	Human	PMID:23236378
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q96J02	Human	PMID:23236378
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q96J02	Human	PMID:23886940
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:O60760	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:O75886	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:O95817	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:P21580	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q8IWZ5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q96DC9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q96GG9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q96LR5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q9UBU8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q9UBU8-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q96J02	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:O00308	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:O43189	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:O60760	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:O75886	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:O95208-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:O95817	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:O95967	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:P21580	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:P32320	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:P41182	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:P51668	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:P54646	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:P57075-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:P62837	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:P62987	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:P63244	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q86YD7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q8IVM0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q969T4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q96CV9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q96DC9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q96GG9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q96GM5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q96LR5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q96PU5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q9BSL1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q9H0E2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q9H0M0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q9NS91	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q9NZC7-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q9UGI0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:Q9UJ41-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ARRDC3	IPI	UniProtKB:P46934	Human	PMID:35044719
Cellular Component	GO:0005768	endosome	ARRDC3	IDA		Human	PMID:23236378
Cellular Component	GO:0005886	plasma membrane	ARRDC3	IDA		Human	PMID:23236378
Biological Process	GO:0060613	fat pad development	Arrdc3	IMP	MGI:MGI:3877613	Mouse	PMID:21982743
Biological Process	GO:0031649	heat generation	Arrdc3	IMP	MGI:MGI:3877613	Mouse	PMID:21982743
Biological Process	GO:0071878	negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway	Arrdc3	IMP	MGI:MGI:3877613	Mouse	PMID:21982743
Biological Process	GO:0120163	negative regulation of cold-induced thermogenesis	Arrdc3	IMP		Mouse	MGI:MGI:5302794|PMID:21982743
Biological Process	GO:0031651	negative regulation of heat generation	Arrdc3	IMP	MGI:MGI:3877613	Mouse	PMID:21982743
Biological Process	GO:0090327	negative regulation of locomotion involved in locomotory behavior	Arrdc3	IMP	MGI:MGI:3877613	Mouse	PMID:21982743
Biological Process	GO:0035332	positive regulation of hippo signaling	ARRDC3	IMP		Human	PMID:24114784
Biological Process	GO:0035332	positive regulation of hippo signaling	ARRDC3	IMP		Human	PMID:29364502
Biological Process	GO:0051443	positive regulation of ubiquitin-protein transferase activity	ARRDC3	IPI	UniProtKB:Q96PU5	Human	PMID:23236378
Biological Process	GO:0043588	skin development	Arrdc3	IMP	MGI:MGI:3883794	Mouse	PMID:23236378
Biological Process	GO:0001659	temperature homeostasis	Arrdc3	IMP	MGI:MGI:3877613	Mouse	PMID:21982743

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern