Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARHGAP42
  • Mouse genes Arhgap42
  • Rat genes Arhgap42
  • Zfish genes arhgap42a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arhgap42

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	ARHGAP42	IDA		Human	PMID:24335996
Molecular Function	GO:0005096	GTPase activator activity	Arhgap42	IDA		Mouse	PMID:24335996
Biological Process	GO:0090630	activation of GTPase activity	ARHGAP42	IDA		Human	PMID:24335996
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	Arhgap42	IMP	MGI:MGI:3871380	Mouse	PMID:24335996
Biological Process	GO:0003085	negative regulation of systemic arterial blood pressure	Arhgap42	IGI	MGI:MGI:1096342	Mouse	PMID:24335996
Biological Process	GO:1904694	negative regulation of vascular associated smooth muscle contraction	Arhgap42	IMP	MGI:MGI:3871380	Mouse	PMID:24335996

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern