Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARHGAP18
  • Mouse genes Arhgap18
  • Rat genes Arhgap18
  • Zfish genes arhgap18
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arhgap18

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	ARHGAP18	HDA		Human	PMID:25468996
Molecular Function	GO:0005096	GTPase activator activity	ARHGAP18	IMP		Human	PMID:21865595
Cellular Component	GO:0005737	cytoplasm	ARHGAP18	IMP		Human	PMID:21865595
Cellular Component	GO:0005881	cytoplasmic microtubule	ARHGAP18	IDA		Human	PMID:28251925
Cellular Component	GO:0005829	cytosol	ARHGAP18	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	ARHGAP18	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ARHGAP18	IDA		Human	GO_REF:0000052
Cellular Component	GO:0001726	ruffle	ARHGAP18	IDA		Human	PMID:28251925
Biological Process	GO:1903671	negative regulation of sprouting angiogenesis	arhgap18	IMP	ZFIN:ZDB-MRPHLNO-150930-1	Zfish	PMID:25425145
Biological Process	GO:1903671	negative regulation of sprouting angiogenesis	arhgap18	IMP	ZFIN:ZDB-MRPHLNO-150930-2	Zfish	PMID:25425145
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	ARHGAP18	IMP		Human	PMID:21865595
Biological Process	GO:0030833	regulation of actin filament polymerization	ARHGAP18	IMP		Human	PMID:21865595
Biological Process	GO:2000145	regulation of cell motility	ARHGAP18	IMP		Human	PMID:21865595
Biological Process	GO:0008360	regulation of cell shape	ARHGAP18	IMP		Human	PMID:21865595
Biological Process	GO:0051056	regulation of small GTPase mediated signal transduction	ARHGAP18	IMP		Human	PMID:21865595
Biological Process	GO:0007264	small GTPase mediated signal transduction	ARHGAP18	IMP		Human	PMID:21865595

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern