Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AREL1
  • Mouse genes Arel1
  • Rat genes Arel1
  • Zfish genes arel1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arel1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	AREL1	IPI	UniProtKB:O43236,UniProtKB:O43464,UniProtKB:Q9NR28	Human	PMID:23479728
Molecular Function	GO:0005515	protein binding	AREL1	IPI	UniProtKB:O14508	Human	PMID:31578312
Molecular Function	GO:0005515	protein binding	Arel1	IPI	UniProtKB:P28661,UniProtKB:Q9JIQ3,UniProtKB:Q9JIY5	Mouse	MGI:MGI:5498443|PMID:23479728
Molecular Function	GO:0005515	protein binding	Arel1	IPI	UniProtKB:O35717	Mouse	MGI:MGI:6369908|PMID:31578312
Molecular Function	GO:0061630	ubiquitin protein ligase activity	AREL1	IDA		Human	PMID:25752577
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	AREL1	IDA		Human	PMID:23479728
Cellular Component	GO:0005829	cytosol	AREL1	IDA		Human	PMID:23479728
Biological Process	GO:0043066	negative regulation of apoptotic process	AREL1	IDA		Human	PMID:23479728
Biological Process	GO:0070979	protein K11-linked ubiquitination	AREL1	IDA		Human	PMID:25752577
Biological Process	GO:1990390	protein K33-linked ubiquitination	AREL1	IDA		Human	PMID:25752577
Biological Process	GO:0016567	protein ubiquitination	AREL1	IDA		Human	PMID:31578312
Biological Process	GO:0016567	protein ubiquitination	Arel1	IMP		Mouse	MGI:MGI:6369908|PMID:31578312
Biological Process	GO:0050727	regulation of inflammatory response	Arel1	IMP		Mouse	MGI:MGI:6369908|PMID:31578312
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	AREL1	IDA		Human	PMID:23479728
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	Arel1	IDA		Mouse	MGI:MGI:5498443|PMID:23479728

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern