Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ARAP1
  • Mouse genes Arap1
  • Rat genes Arap1
  • Zfish genes arap1a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Arap1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	ARAP1	IDA		Human	PMID:11804590
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	ARAP1	IDA		Human	PMID:11804589
Molecular Function	GO:0005515	protein binding	ARAP1	IPI	UniProtKB:P27958:PRO_0000037576	Human	PMID:15607035
Molecular Function	GO:0005515	protein binding	ARAP1	IPI	UniProtKB:P12956	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	ARAP1	IPI	UniProtKB:O00220	Human	PMID:18165900
Molecular Function	GO:0005515	protein binding	ARAP1	IPI	UniProtKB:P46108	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	ARAP1	IPI	UniProtKB:P46108	Human	PMID:35044719
Molecular Function	GO:0031702	type 1 angiotensin receptor binding	Arap1	IPI	RGD:2070	Rat	PMID:14559250|RGD:2316188
Cellular Component	GO:0031410	cytoplasmic vesicle	Arap1	IDA		Rat	PMID:14559250|RGD:2316188
Cellular Component	GO:0005829	cytosol	ARAP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	ARAP1	IDA		Human	PMID:11804590
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ARAP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ARAP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ARAP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Arap1	IDA		Rat	PMID:14559250|RGD:2316188
Cellular Component	GO:0005802	trans-Golgi network	Arap1	IDA		Rat	PMID:14559250|RGD:2316188
Biological Process	GO:0051497	negative regulation of stress fiber assembly	ARAP1	IMP		Human	PMID:11804590
Biological Process	GO:0051491	positive regulation of filopodium assembly	ARAP1	IMP		Human	PMID:11804590
Biological Process	GO:0043547	positive regulation of GTPase activity	ARAP1	IDA		Human	PMID:11804590
Biological Process	GO:0001921	positive regulation of receptor recycling	Arap1	IDA		Rat	PMID:14559250|RGD:2316188
Biological Process	GO:0008360	regulation of cell shape	ARAP1	IMP		Human	PMID:11804590

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern