Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes APLP1
  • Mouse genes Aplp1
  • Rat genes Aplp1
  • Zfish genes aplp1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aplp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031694	alpha-2A adrenergic receptor binding	APLP1	IPI	UniProtKB:P08913	Human	PMID:16531006
Molecular Function	GO:0031695	alpha-2B adrenergic receptor binding	APLP1	IPI	UniProtKB:P18089	Human	PMID:16531006
Molecular Function	GO:0031696	alpha-2C adrenergic receptor binding	APLP1	IPI	UniProtKB:P18825	Human	PMID:16531006
Molecular Function	GO:0042802	identical protein binding	APLP1	IPI	UniProtKB:P51693	Human	PMID:16193067
Molecular Function	GO:0042802	identical protein binding	APLP1	IPI	UniProtKB:P51693	Human	PMID:21930949
Molecular Function	GO:0005515	protein binding	APLP1	IPI	UniProtKB:P17028	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	APLP1	IPI	UniProtKB:P05067-4	Human	PMID:16193067
Molecular Function	GO:0005515	protein binding	APLP1	IPI	UniProtKB:Q06481	Human	PMID:16193067
Molecular Function	GO:0005515	protein binding	APLP1	IPI	UniProtKB:Q93074	Human	PMID:21293490
Molecular Function	GO:0005515	protein binding	APLP1	IPI	UniProtKB:Q9UBQ0-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Aplp1	IPI	UniProtKB:P12023	Mouse	MGI:MGI:3829123|PMID:17934213
Molecular Function	GO:0005515	protein binding	Aplp1	IPI	UniProtKB:P12023	Mouse	MGI:MGI:4399021|PMID:16193067
Molecular Function	GO:0005515	protein binding	Aplp1	IPI	UniProtKB:P97318	Mouse	MGI:MGI:1343748|PMID:10460257
Molecular Function	GO:0005515	protein binding	Aplp1	IPI	UniProtKB:Q8C142	Mouse	MGI:MGI:3762243|PMID:17727637
Molecular Function	GO:0005515	protein binding	Aplp1	IPI	UniProtKB:P97318	Mouse	MGI:MGI:2675568|PMID:12826668
Molecular Function	GO:0005515	protein binding	Aplp1	IPI	PR:P70166	Mouse	PMID:16314516
Molecular Function	GO:0005515	protein binding	Aplp1	IPI	PR:Q9QXJ1	Mouse	PMID:8894693
Molecular Function	GO:0005515	protein binding	Aplp1	IPI	RGD:2122	Rat	PMID:9461550|RGD:634556
Molecular Function	GO:0005515	protein binding	Aplp1	IPI	RGD:620853	Rat	PMID:9461550|RGD:634556
Cellular Component	GO:0005794	Golgi apparatus	APLP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	Aplp1	IDA		Mouse	MGI:MGI:51815|PMID:1279693
Cellular Component	GO:0016020	membrane	Aplp1	IDA		Mouse	PMID:16314516
Cellular Component	GO:0005654	nucleoplasm	APLP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0048471	perinuclear region of cytoplasm	APLP1	IDA		Human	PMID:16531006
Cellular Component	GO:0005886	plasma membrane	APLP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	APLP1	IDA		Human	PMID:16531006
Biological Process	GO:0071874	cellular response to norepinephrine stimulus	APLP1	IDA		Human	PMID:16531006
Biological Process	GO:0030198	extracellular matrix organization	Aplp1	IGI	MGI:MGI:88047,MGI:MGI:88059	Mouse	PMID:15385965
Biological Process	GO:0030900	forebrain development	Aplp1	IGI	MGI:MGI:88047,MGI:MGI:88059	Mouse	PMID:15385965
Biological Process	GO:0006378	mRNA polyadenylation	Aplp1	IDA		Mouse	PMID:16314516
Biological Process	GO:0106072	negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	APLP1	IDA		Human	PMID:16531006
Biological Process	GO:0006417	regulation of translation	Aplp1	IDA		Mouse	PMID:16314516

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern