Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AP4M1
  • Mouse genes Ap4m1
  • Rat genes Ap4m1
  • Zfish genes ap4m1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ap4m1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	AP4M1	IPI	UniProtKB:Q96K76	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AP4M1	IPI	UniProtKB:Q9UK23	Human	PMID:26544806
Molecular Function	GO:0005515	protein binding	AP4M1	IPI	UniProtKB:Q7Z3C6	Human	PMID:29180427
Molecular Function	GO:0005515	protein binding	AP4M1	IPI	UniProtKB:Q9UJC3	Human	PMID:32073997
Molecular Function	GO:0005515	protein binding	AP4M1	IPI	UniProtKB:P49354	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AP4M1	IPI	UniProtKB:Q96K76-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ap4m1	IPI	UniProtKB:P23818|UniProtKB:P23819	Mouse	MGI:MGI:3794899|PMID:18341993
Molecular Function	GO:0005515	protein binding	Ap4m1	IPI	UniProtKB:Q9JJV5	Mouse	MGI:MGI:3794899|PMID:18341993
Molecular Function	GO:0019904	protein domain specific binding	AP4M1	IDA		Human	PMID:11139587
Molecular Function	GO:0019904	protein domain specific binding	AP4M1	IDA		Human	PMID:26544806
Cellular Component	GO:0030124	AP-4 adaptor complex	AP4M1	IDA		Human	PMID:10066790
Cellular Component	GO:0030124	AP-4 adaptor complex	AP4M1	IDA		Human	PMID:11802162
Cellular Component	GO:0030124	AP-4 adaptor complex	AP4M1	IDA		Human	PMID:29180427
Cellular Component	GO:0070062	extracellular exosome	AP4M1	HDA		Human	PMID:19056867
Cellular Component	GO:0005802	trans-Golgi network	AP4M1	IDA		Human	PMID:20230749
Cellular Component	GO:0005802	trans-Golgi network	AP4M1	IDA		Human	PMID:32073997
Cellular Component	GO:0005802	trans-Golgi network	AP4M1	IDA		Human	PMID:29180427
Biological Process	GO:0000045	autophagosome assembly	AP4M1	IMP		Human	PMID:29180427
Biological Process	GO:0006895	Golgi to endosome transport	AP4M1	IMP		Human	PMID:20230749
Biological Process	GO:0090160	Golgi to lysosome transport	AP4M1	IDA		Human	PMID:11139587
Biological Process	GO:0006886	intracellular protein transport	AP4M1	IMP		Human	PMID:20230749
Biological Process	GO:0006886	intracellular protein transport	AP4M1	IMP		Human	PMID:29180427
Biological Process	GO:0008104	protein localization	Ap4m1	IMP		Mouse	MGI:MGI:3794899|PMID:18341993
Biological Process	GO:0006605	protein targeting	AP4M1	IDA		Human	PMID:20230749
Biological Process	GO:0006605	protein targeting	Ap4m1	IMP		Mouse	MGI:MGI:3794899|PMID:18341993
Biological Process	GO:0006622	protein targeting to lysosome	AP4M1	IDA		Human	PMID:11139587

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern