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Ap4m1
Gene Detail
Symbol

Name
ID
Ap4m1
adaptor-related protein complex AP-4, mu 1
MGI:1337063
Synonyms
4930443L05Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 5
76.98 cM, cytoband G1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:138172002-138178708 bp, + strand
From VEGA annotation of GRCm38

  6707 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3467  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: AP4M1
Protein SuperFamily: adaptor protein complex, mu subunit
Gene Tree: Ap4m1

Human
homologs
AP4M1, adaptor-related protein complex 4, mu 1 subunit
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 9179
neXtProt AC: NX_O00189

Human Synonyms: CPSQ3, MU-4, MU-ARP2, SPG50

Human Chr (Location): 7q22.1; chr7:100101412-100107180 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human AP4M1

Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Gene trapped(8) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ap4m1 interacts with 220 markers (Mir1a-1, Mir1a-2, Mir18, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process Golgi to endosome transport, intracellular protein transport, ...
Component clathrin adaptor complex, coated pit, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (16)    Tissues (16)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 16
cDNA source data(36)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ap4m1 ; ZFIN ap4m1    NEW 
Molecular
reagents
All nucleic(37) cDNA(36) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000022671 (Evidence)
Ensembl Gene Model ENSMUSG00000019518 (Evidence)
Entrez Gene 11781 (Evidence)
UniGene 113205
DFCI TC1580461
NIA Mouse Gene Index U042703
Consensus CDS Project CCDS19794.1
International Mouse Phenotyping Consortium Status Ap4m1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022671 VEGA Gene Model | MGI Sequence Detail 6707 C57BL/6J ±  kb
transcript OTTMUST00000054326 VEGA | MGI Sequence Detail 1758 Not Applicable 
polypeptide OTTMUSP00000025920 VEGA | MGI Sequence Detail 449 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(4) UniProt(4)
Polymorphisms
SNPs within 2kb(58 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR022775 AP complex, mu/sigma subunit
InterPro IPR001392 Clathrin adaptor, mu subunit
InterPro IPR018240 Clathrin adaptor, mu subunit, conserved site
InterPro IPR008968 Clathrin adaptor, mu subunit, C-terminal
InterPro IPR011012 Longin-like domain
Protein Ontology PR:000004113 AP-4 complex subunit mu-1
References
(Earliest) J:48443 Odorizzi G, et al., The AP-3 complex: a coat of many colours. Trends Cell Biol. 1998 Jul;8(7):282-8
(Latest) J:176132 O'Leary J, et al., Global analysis of gene expression in the developing brain of gtf2ird1 knockout mice. PLoS One. 2011;6(8):e23868
All references(33)
Other
accession IDs
MGI:1918896

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory