Ap4m1
Gene Detail

Symbol Name ID

Ap4m1 adaptor-related protein complex AP-4, mu 1 MGI:1337063

Synonyms

4930443L05Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 5

76.98 cM, cytoband G1
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr5:138172002-138178708 bp, + strand From VEGA annotation of GRCm38   6707 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:3467  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: adaptor protein complex, mu subunit
Gene Tree: Ap4m1

Human homologs

Human Homolog		AP4M1, adaptor-related protein complex 4, mu 1 subunit
NCBI Gene ID		9179
neXtProt AC		NX_O00189
Human Synonyms		CPSQ3, MU-4, MU-ARP2, SPG50
Human Chr (Location)		7q22.1; chr7:99699130-99704803 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human AP4M1

Alleles and phenotypes

All alleles(12) : Targeted(4) Gene trapped(8)

Gene Ontology (GO) classifications

All GO classifications: (13 annotations)

Process	Golgi to endosome transport, intracellular protein transport, ...
Component	clathrin adaptor complex, coated pit, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (16)    Tissues (16)   
Theiler Stages: 20, 22, 24, 26, 28

Assay Type	Results
RNA in situ	16

cDNA source data(36)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(37) cDNA(36) Primer pair(1)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000022671 (Evidence)
Ensembl Gene Model	ENSMUSG00000019518 (Evidence)
Entrez Gene	11781 (Evidence)
UniGene	113205
DFCI	TC1580461
NIA Mouse Gene Index	U042703
Consensus CDS Project	CCDS19794.1
International Mouse Knockout Project Status	Ap4m1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000022671	VEGA Gene Model | MGI Sequence Detail	6707	C57BL/6J
transcript	OTTMUST00000054326	VEGA | MGI Sequence Detail	1758	Not Applicable
polypeptide	OTTMUSP00000025920	VEGA | MGI Sequence Detail	449	Not Applicable

All sequences(37) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(43 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR022775	AP complex, mu/sigma subunit
InterPro	IPR001392	Clathrin adaptor, mu subunit
InterPro	IPR018240	Clathrin adaptor, mu subunit, conserved site
InterPro	IPR008968	Clathrin adaptor, mu subunit, C-terminal
InterPro	IPR011012	Longin-like domain
Protein Ontology	PR:000004113	AP-4 complex subunit mu-1

References

(Earliest) J:48443 Odorizzi G, et al., The AP-3 complex: a coat of many colours. Trends Cell Biol. 1998 Jul;8(7):282-8
(Latest) J:176132 O'Leary J, et al., Global analysis of gene expression in the developing brain of gtf2ird1 knockout mice. PLoS One. 2011;6(8):e23868
All references(35)

Other accession IDs

MGI:1918896