Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AOX1
  • Mouse genes Aox1
  • Rat genes Aox1
  • Zfish genes aox5,aox6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aox1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051537	2 iron, 2 sulfur cluster binding	AOX1	IDA		Human	PMID:26322824
Molecular Function	GO:0051537	2 iron, 2 sulfur cluster binding	AOX1	IDA		Human	PMID:26842593
Molecular Function	GO:0004031	aldehyde oxidase activity	AOX1	IDA		Human	PMID:22279051
Molecular Function	GO:0004031	aldehyde oxidase activity	AOX1	IDA		Human	PMID:26842593
Molecular Function	GO:0004031	aldehyde oxidase activity	Aox1	IDA		Mouse	MGI:MGI:1334798|PMID:10190983
Molecular Function	GO:0004031	aldehyde oxidase activity	Aox1	IDA		Mouse	MGI:MGI:3844160|PMID:19401776
Molecular Function	GO:0004031	aldehyde oxidase activity	Aox1	IDA		Mouse	PMID:6372555
Molecular Function	GO:0004031	aldehyde oxidase activity	Aox1	IDA		Mouse	PMID:518535
Molecular Function	GO:0004031	aldehyde oxidase activity	Aox1	IDA		Rat	PMID:9920943|RGD:632256
Molecular Function	GO:0050660	flavin adenine dinucleotide binding	AOX1	IDA		Human	PMID:26322824
Molecular Function	GO:0050660	flavin adenine dinucleotide binding	AOX1	IDA		Human	PMID:26842593
Molecular Function	GO:0042802	identical protein binding	AOX1	IPI	UniProtKB:Q06278	Human	PMID:26322824
Molecular Function	GO:0005506	iron ion binding	AOX1	IDA		Human	PMID:26322824
Molecular Function	GO:0005506	iron ion binding	AOX1	IDA		Human	PMID:26842593
Molecular Function	GO:0043546	molybdopterin cofactor binding	AOX1	IDA		Human	PMID:26322824
Molecular Function	GO:0043546	molybdopterin cofactor binding	AOX1	IDA		Human	PMID:26842593
Molecular Function	GO:0042803	protein homodimerization activity	AOX1	IDA		Human	PMID:26322824
Molecular Function	GO:0042803	protein homodimerization activity	AOX1	IDA		Human	PMID:26842593
Molecular Function	GO:0042803	protein homodimerization activity	Aox1	IDA		Mouse	MGI:MGI:3844160|PMID:19401776
Cellular Component	GO:0005737	cytoplasm	aox5	IDA		Zfish	PMID:18417109
Cellular Component	GO:0005829	cytosol	AOX1	IDA		Human	PMID:20444863
Cellular Component	GO:0005829	cytosol	AOX1	IDA		Human	PMID:23857892
Cellular Component	GO:0005829	cytosol	Aox1	IDA		Mouse	MGI:MGI:1341477|PMID:10377246
Cellular Component	GO:0070062	extracellular exosome	AOX1	HDA		Human	PMID:19056867
Biological Process	GO:0006805	xenobiotic metabolic process	AOX1	IDA		Human	PMID:20444863
Biological Process	GO:0006805	xenobiotic metabolic process	AOX1	IDA		Human	PMID:22031625
Biological Process	GO:0006805	xenobiotic metabolic process	AOX1	IDA		Human	PMID:22522748
Biological Process	GO:0006805	xenobiotic metabolic process	AOX1	IDA		Human	PMID:23857892
Biological Process	GO:0006805	xenobiotic metabolic process	Aox1	IDA		Mouse	MGI:MGI:5553225|PMID:23462233

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern