Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ANO2
  • Mouse genes Ano2
  • Rat genes Ano2
  • Zfish genes ano2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ano2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Ano2	IPI	PR:Q8CFW1	Mouse	PMID:23576756
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	ANO2	IDA		Human	PMID:19474308
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	ANO2	IDA		Human	PMID:21984732
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	Ano2	IDA		Mouse	MGI:MGI:4412429|PMID:19561302
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	Ano2	IDA		Mouse	MGI:MGI:4413547|PMID:19475416
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	Ano2	IDA		Mouse	MGI:MGI:5448512|PMID:22075693
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	Ano2	IDA		Mouse	MGI:MGI:3848635|PMID:19474308
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	Ano2	IMP	MGI:MGI:5052299	Mouse	PMID:21516098
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	Ano2	IDA		Mouse	PMID:20056604
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	Ano2	IDA		Mouse	PMID:23532839
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	Ano2	IDA		Rat	PMID:24081981|RGD:9684847
Molecular Function	GO:0005229	intracellular calcium activated chloride channel activity	Ano2	IMP		Rat	PMID:24081981|RGD:9684847
Molecular Function	GO:0005515	protein binding	ANO2	IPI	UniProtKB:Q12959	Human	PMID:30126976
Molecular Function	GO:0005515	protein binding	Ano2	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:3848635|PMID:19474308
Molecular Function	GO:0005515	protein binding	Ano2	IPI	PR:Q8BHY3	Mouse	PMID:23576756
Cellular Component	GO:0098978	glutamatergic synapse	Ano2	IDA		Mouse	PMID:19474308
Cellular Component	GO:0043005	neuron projection	Ano2	IDA		Mouse	PMID:21516098
Cellular Component	GO:0097730	non-motile cilium	Ano2	IDA		Mouse	PMID:21516098
Cellular Component	GO:0005654	nucleoplasm	ANO2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ANO2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Ano2	IDA		Mouse	MGI:MGI:3848635|PMID:19474308
Cellular Component	GO:0005886	plasma membrane	Ano2	IDA		Mouse	PMID:20056604
Cellular Component	GO:0005886	plasma membrane	Ano2	IDA		Rat	PMID:24081981|RGD:9684847
Cellular Component	GO:0042734	presynaptic membrane	Ano2	IDA		Mouse	PMID:19474308
Biological Process	GO:0006821	chloride transport	Ano2	IMP	MGI:MGI:5052299	Mouse	PMID:21516098
Biological Process	GO:0006821	chloride transport	Ano2	IDA		Mouse	PMID:23532839
Biological Process	GO:0006821	chloride transport	Ano2	IDA		Mouse	PMID:20056604
Biological Process	GO:0051649	establishment of localization in cell	Ano2	IDA		Mouse	PMID:23532839
Biological Process	GO:0051649	establishment of localization in cell	Ano2	IMP	MGI:MGI:5052299	Mouse	PMID:21516098

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern