Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALKBH5
  • Mouse genes Alkbh5
  • Rat genes Alkbh5
  • Zfish genes alkbh5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Alkbh5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016706	2-oxoglutarate-dependent dioxygenase activity	ALKBH5	IDA		Human	PMID:21264265
Molecular Function	GO:1990931	mRNA N6-methyladenosine dioxygenase activity	ALKBH5	IDA		Human	PMID:23177736
Molecular Function	GO:1990931	mRNA N6-methyladenosine dioxygenase activity	ALKBH5	IDA		Human	PMID:24616105
Molecular Function	GO:1990931	mRNA N6-methyladenosine dioxygenase activity	Alkbh5	IMP		Mouse	MGI:MGI:6111276|PMID:29279410
Molecular Function	GO:0035515	oxidative RNA demethylase activity	alkbh5	IDA		Zfish	PMID:24561204
Molecular Function	GO:0003723	RNA binding	ALKBH5	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	ALKBH5	HDA		Human	PMID:22681889
Cellular Component	GO:0005829	cytosol	ALKBH5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	ALKBH5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	ALKBH5	IDA		Human	PMID:23177736
Cellular Component	GO:0016607	nuclear speck	Alkbh5	IMP		Mouse	MGI:MGI:6111276|PMID:29279410
Cellular Component	GO:0005654	nucleoplasm	ALKBH5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ALKBH5	IDA		Human	PMID:21264265
Biological Process	GO:0006406	mRNA export from nucleus	ALKBH5	IMP		Human	PMID:23177736
Biological Process	GO:0006397	mRNA processing	ALKBH5	IMP		Human	PMID:23177736
Biological Process	GO:0035553	oxidative single-stranded RNA demethylation	ALKBH5	IDA		Human	PMID:23177736
Biological Process	GO:0035553	oxidative single-stranded RNA demethylation	ALKBH5	IDA		Human	PMID:24616105
Biological Process	GO:0035553	oxidative single-stranded RNA demethylation	Alkbh5	IMP		Mouse	MGI:MGI:6111276|PMID:29279410
Biological Process	GO:0043488	regulation of mRNA stability	Alkbh5	IMP		Mouse	MGI:MGI:6111276|PMID:29279410
Biological Process	GO:0001666	response to hypoxia	ALKBH5	IDA		Human	PMID:21264265
Biological Process	GO:0007283	spermatogenesis	Alkbh5	IMP		Mouse	MGI:MGI:5471209|PMID:23177736
Biological Process	GO:0007283	spermatogenesis	Alkbh5	IMP		Mouse	MGI:MGI:6111276|PMID:29279410

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern