Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALDH4A1
  • Mouse genes Aldh4a1
  • Rat genes Aldh4a1
  • Zfish genes aldh4a1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aldh4a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003842	1-pyrroline-5-carboxylate dehydrogenase activity	Aldh4a1	IDA		Mouse	PMID:23928095
Molecular Function	GO:0004029	aldehyde dehydrogenase (NAD+) activity	ALDH4A1	IDA		Human	PMID:4015840
Molecular Function	GO:0042802	identical protein binding	ALDH4A1	IPI	UniProtKB:P30038	Human	PMID:22516612
Molecular Function	GO:0005515	protein binding	ALDH4A1	IPI	UniProtKB:Q09028	Human	PMID:32814053
Cellular Component	GO:0005829	cytosol	ALDH4A1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	ALDH4A1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Aldh4a1	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Aldh4a1	HDA		Mouse	PMID:18614015

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern