Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ALDH1A3
  • Mouse genes Aldh1a3
  • Rat genes Aldh1a3
  • Zfish genes aldh1a3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aldh1a3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004029	aldehyde dehydrogenase (NAD+) activity	Aldh1a3	IDA		Mouse	PMID:11013254
Molecular Function	GO:0004029	aldehyde dehydrogenase (NAD+) activity	Aldh1a3	IDA		Mouse	PMID:16241904
Molecular Function	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	ALDH1A3	IDA		Human	PMID:11585737
Molecular Function	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	Aldh1a3	IDA		Mouse	PMID:11044606
Molecular Function	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	Aldh1a3	IDA		Rat	PMID:11306051|RGD:634541
Molecular Function	GO:0070403	NAD+ binding	Aldh1a3	IDA		Mouse	PMID:16241904
Molecular Function	GO:0042803	protein homodimerization activity	ALDH1A3	IDA		Human	PMID:11585737
Molecular Function	GO:0001758	retinal dehydrogenase activity	ALDH1A3	IDA		Human	PMID:27759097
Molecular Function	GO:0070324	thyroid hormone binding	Aldh1a3	IPI	CHEBI:18258	Mouse	PMID:16241904
Cellular Component	GO:0005737	cytoplasm	ALDH1A3	IDA		Human	PMID:11585737
Cellular Component	GO:0005737	cytoplasm	Aldh1a3	IDA		Mouse	PMID:16615129
Cellular Component	GO:0070062	extracellular exosome	ALDH1A3	HDA		Human	PMID:23533145
Biological Process	GO:0006915	apoptotic process	Aldh1a3	IMP	MGI:MGI:3043947	Mouse	PMID:16207763
Biological Process	GO:0006915	apoptotic process	Aldh1a3	IGI	MGI:MGI:1353450	Mouse	PMID:16611695
Biological Process	GO:0006915	apoptotic process	Aldh1a3	IGI	MGI:MGI:1353450	Mouse	PMID:16207763
Biological Process	GO:0031076	embryonic camera-type eye development	Aldh1a3	IMP		Mouse	MGI:MGI:3042765|PMID:14623956
Biological Process	GO:0031076	embryonic camera-type eye development	Aldh1a3	IGI	MGI:MGI:107928	Mouse	PMID:17184764
Biological Process	GO:0048048	embryonic eye morphogenesis	Aldh1a3	IMP	MGI:MGI:3043947	Mouse	PMID:16207763
Biological Process	GO:0048048	embryonic eye morphogenesis	Aldh1a3	IGI	MGI:MGI:1353450	Mouse	PMID:16611695
Biological Process	GO:0048048	embryonic eye morphogenesis	Aldh1a3	IGI	MGI:MGI:1353450	Mouse	PMID:16207763
Biological Process	GO:0048048	embryonic eye morphogenesis	Aldh1a3	IMP		Mouse	PMID:16611695
Biological Process	GO:0060324	face development	Aldh1a3	IGI	MGI:MGI:107928	Mouse	PMID:17184764
Biological Process	GO:0070384	Harderian gland development	Aldh1a3	IMP		Mouse	MGI:MGI:3042765|PMID:14623956
Biological Process	GO:0042472	inner ear morphogenesis	Aldh1a3	IMP	MGI:MGI:3043947	Mouse	PMID:23536097
Biological Process	GO:0001822	kidney development	Aldh1a3	IEP		Rat	PMID:15567713|RGD:2306322
Biological Process	GO:0007626	locomotory behavior	Aldh1a3	IMP	MGI:MGI:3043947	Mouse	PMID:23536097
Biological Process	GO:0050885	neuromuscular process controlling balance	Aldh1a3	IMP	MGI:MGI:3043947	Mouse	PMID:23536097
Biological Process	GO:0043584	nose development	Aldh1a3	IMP		Mouse	MGI:MGI:3042765|PMID:14623956
Biological Process	GO:0021768	nucleus accumbens development	Aldh1a3	IMP	MGI:MGI:3512079	Mouse	PMID:17207476
Biological Process	GO:0060166	olfactory pit development	Aldh1a3	IMP	MGI:MGI:3512079	Mouse	PMID:17207476
Biological Process	GO:0002072	optic cup morphogenesis involved in camera-type eye development	Aldh1a3	IGI	MGI:MGI:1353450	Mouse	PMID:16611695
Biological Process	GO:0021983	pituitary gland development	Aldh1a3	IEP		Rat	PMID:17180597|RGD:2306413
Biological Process	GO:0043065	positive regulation of apoptotic process	Aldh1a3	IMP	MGI:MGI:3043947	Mouse	PMID:16207763
Biological Process	GO:0043065	positive regulation of apoptotic process	Aldh1a3	IGI	MGI:MGI:1353450	Mouse	PMID:16611695
Biological Process	GO:0043065	positive regulation of apoptotic process	Aldh1a3	IGI	MGI:MGI:1353450	Mouse	PMID:16207763
Biological Process	GO:0051289	protein homotetramerization	ALDH1A3	IDA		Human	PMID:27759097
Biological Process	GO:0009410	response to xenobiotic stimulus	Aldh1a3	IEP		Rat	PMID:11306051|RGD:634541
Biological Process	GO:0042574	retinal metabolic process	ALDH1A3	IDA		Human	PMID:11585737
Biological Process	GO:0002138	retinoic acid biosynthetic process	ALDH1A3	IDA		Human	PMID:27759097
Biological Process	GO:0002138	retinoic acid biosynthetic process	Aldh1a3	IMP		Mouse	MGI:MGI:3042765|PMID:14623956
Biological Process	GO:0002138	retinoic acid biosynthetic process	Aldh1a3	IDA		Mouse	PMID:16241904
Biological Process	GO:0002138	retinoic acid biosynthetic process	Aldh1a3	IDA		Mouse	PMID:11013254
Biological Process	GO:0002138	retinoic acid biosynthetic process	Aldh1a3	IDA		Mouse	PMID:11044606
Biological Process	GO:0002138	retinoic acid biosynthetic process	Aldh1a3	IEP		Rat	PMID:15950969|RGD:6771322
Biological Process	GO:0002138	retinoic acid biosynthetic process	Aldh1a3	IMP		Rat	PMID:21138835|RGD:6771354
Biological Process	GO:0042573	retinoic acid metabolic process	ALDH1A3	IDA		Human	PMID:11585737
Biological Process	GO:0042573	retinoic acid metabolic process	Aldh1a3	IGI	MGI:MGI:1353450	Mouse	PMID:16207763
Biological Process	GO:0042573	retinoic acid metabolic process	Aldh1a3	IMP	MGI:MGI:3043947	Mouse	PMID:16207763
Biological Process	GO:0042573	retinoic acid metabolic process	Aldh1a3	IMP	MGI:MGI:3512079	Mouse	PMID:17207476
Biological Process	GO:0060013	righting reflex	Aldh1a3	IMP	MGI:MGI:3043947	Mouse	PMID:23536097

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern