Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AKT1S1
  • Mouse genes Akt1s1
  • Rat genes Akt1s1
  • Zfish genes akt1s1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Akt1s1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	AKT1S1	IPI	UniProtKB:Q04917	Human	PMID:12524439
Molecular Function	GO:0005515	protein binding	AKT1S1	IPI	UniProtKB:Q8N122	Human	PMID:17386266
Molecular Function	GO:0005515	protein binding	AKT1S1	IPI	UniProtKB:P29311	Human	PMID:17604271
Molecular Function	GO:0005515	protein binding	AKT1S1	IPI	UniProtKB:Q04917	Human	PMID:17979178
Molecular Function	GO:0005515	protein binding	AKT1S1	IPI	UniProtKB:P29311	Human	PMID:19648646
Molecular Function	GO:0005515	protein binding	AKT1S1	IPI	UniProtKB:Q04917	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Akt1s1	IPI	RGD:3979	Rat	PMID:17457363|RGD:2307106
Cellular Component	GO:0005737	cytoplasm	Akt1s1	IDA		Rat	PMID:17130464|RGD:2307379
Cellular Component	GO:0005829	cytosol	AKT1S1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Akt1s1	IDA		Mouse	MGI:MGI:3693378|PMID:14973226
Cellular Component	GO:0005634	nucleus	Akt1s1	IDA		Rat	PMID:17130464|RGD:2307379
Cellular Component	GO:0032991	protein-containing complex	Akt1s1	IDA		Rat	PMID:17457363|RGD:2307106
Biological Process	GO:0045792	negative regulation of cell size	AKT1S1	IDA		Human	PMID:17386266
Biological Process	GO:0006469	negative regulation of protein kinase activity	AKT1S1	IDA		Human	PMID:17386266
Biological Process	GO:0032007	negative regulation of TOR signaling	AKT1S1	IDA		Human	PMID:17386266
Biological Process	GO:0042981	regulation of apoptotic process	Akt1s1	IDA		Mouse	MGI:MGI:3694286|PMID:16397181
Biological Process	GO:0043523	regulation of neuron apoptotic process	Akt1s1	IDA		Mouse	MGI:MGI:3693378|PMID:14973226

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern