Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AKIRIN2
  • Mouse genes Akirin2
  • Rat genes Akirin2
  • Zfish genes akirin2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Akirin2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	AKIRIN2	IPI	UniProtKB:Q96EB6	Human	PMID:23382074
Molecular Function	GO:0042802	identical protein binding	AKIRIN2	IPI	UniProtKB:Q53H80	Human	PMID:32296183
Molecular Function	GO:0140677	molecular function activator activity	AKIRIN2	IDA		Human	PMID:34711951
Molecular Function	GO:0005515	protein binding	AKIRIN2	IPI	UniProtKB:Q9NZD8	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	AKIRIN2	IPI	UniProtKB:Q9NZD8	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	AKIRIN2	IPI	UniProtKB:Q9NZD8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	AKIRIN2	IPI	UniProtKB:O60504	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AKIRIN2	IPI	UniProtKB:P52597	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AKIRIN2	IPI	UniProtKB:Q14696	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AKIRIN2	IPI	UniProtKB:Q8TDC0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AKIRIN2	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AKIRIN2	IPI	UniProtKB:Q9BPX1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AKIRIN2	IPI	UniProtKB:Q9NZD8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AKIRIN2	IPI	UniProtKB:Q96P70	Human	PMID:34711951
Molecular Function	GO:0005515	protein binding	Akirin2	IPI	UniProtKB:Q61466|UniProtKB:Q9BYH8|UniProtKB:Q9EST8	Mouse	MGI:MGI:5607662|PMID:25107474
Molecular Function	GO:0005515	protein binding	Akirin2	IPI	RGD:61998	Rat	PMID:18460465|RGD:2306009
Molecular Function	GO:0005515	protein binding	Akirin2	IPI	UniProtKB:P31946	Rat	PMID:18460465|RGD:2306009
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	AKIRIN2	IDA		Human	PMID:34711951
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	Akirin2	IDA		Mouse	MGI:MGI:5607662|PMID:25107474
Cellular Component	GO:0005737	cytoplasm	Akirin2	IDA		Mouse	MGI:MGI:6304812|PMID:30801883
Cellular Component	GO:0016020	membrane	Akirin2	IDA		Mouse	MGI:MGI:6304812|PMID:30801883
Cellular Component	GO:0005654	nucleoplasm	AKIRIN2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	AKIRIN2	IDA		Human	PMID:34711951
Cellular Component	GO:0005634	nucleus	AKIRIN2	IDA		Human	PMID:18066067
Cellular Component	GO:0005634	nucleus	Akirin2	IDA		Mouse	MGI:MGI:6304812|PMID:30801883
Cellular Component	GO:0005634	nucleus	Akirin2	IDA		Mouse	MGI:MGI:5607662|PMID:25107474
Cellular Component	GO:0005634	nucleus	Akirin2	IDA		Rat	PMID:18460465|RGD:2306009
Cellular Component	GO:0017053	transcription repressor complex	Akirin2	IDA		Rat	PMID:18460465|RGD:2306009
Biological Process	GO:0021987	cerebral cortex development	Akirin2	IMP		Mouse	MGI:MGI:5811685|PMID:27871306
Biological Process	GO:0042742	defense response to bacterium	Akirin2	IMP		Mouse	MGI:MGI:5607662|PMID:25107474
Biological Process	GO:0009792	embryo development ending in birth or egg hatching	Akirin2	IMP		Mouse	MGI:MGI:3771766|PMID:18066067
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Akirin2	IDA		Rat	PMID:18460465|RGD:2306009
Biological Process	GO:0010629	negative regulation of gene expression	Akirin2	IMP		Rat	PMID:18460465|RGD:2306009
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Akirin2	IDA		Rat	PMID:18460465|RGD:2306009
Biological Process	GO:0071630	nuclear protein quality control by the ubiquitin-proteasome system	AKIRIN2	IDA		Human	PMID:34711951
Biological Process	GO:0002821	positive regulation of adaptive immune response	Akirin2	IMP		Mouse	MGI:MGI:6855963|PMID:26041538
Biological Process	GO:0050871	positive regulation of B cell activation	Akirin2	IMP		Mouse	MGI:MGI:6855963|PMID:26041538
Biological Process	GO:0008284	positive regulation of cell population proliferation	Akirin2	IMP		Rat	PMID:18460465|RGD:2306009
Biological Process	GO:0010950	positive regulation of endopeptidase activity	Akirin2	IMP		Rat	PMID:18460465|RGD:2306009
Biological Process	GO:0045089	positive regulation of innate immune response	Akirin2	IMP		Mouse	MGI:MGI:5607662|PMID:25107474
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Akirin2	IDA		Mouse	MGI:MGI:5607662|PMID:25107474
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Akirin2	IMP	MGI:MGI:3796163	Mouse	PMID:18066067
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Akirin2	IDA		Mouse	MGI:MGI:5607662|PMID:25107474
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Akirin2	IMP	MGI:MGI:3796163	Mouse	PMID:18066067
Biological Process	GO:0031144	proteasome localization	AKIRIN2	IDA		Human	PMID:34711951
Biological Process	GO:0006606	protein import into nucleus	AKIRIN2	IDA		Human	PMID:34711951
Biological Process	GO:0051147	regulation of muscle cell differentiation	Akirin2	IMP		Mouse	MGI:MGI:6304812|PMID:30801883
Biological Process	GO:0032496	response to lipopolysaccharide	Akirin2	IMP	MGI:MGI:3796163	Mouse	PMID:18066067

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern