Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AHCY
  • Mouse genes Ahcyl
  • Rat genes Ahcy
  • Zfish genes ahcy
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ahcyl

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004013	adenosylhomocysteinase activity	AHCY	IDA		Human	PMID:10933798
Molecular Function	GO:0004013	adenosylhomocysteinase activity	Ahcy	IDA		Rat	PMID:11741948|RGD:730275
Molecular Function	GO:0004013	adenosylhomocysteinase activity	Ahcy	IDA		Rat	PMID:11927587|RGD:150521644
Molecular Function	GO:0030554	adenyl nucleotide binding	Ahcy	IDA		Rat	PMID:9291120|RGD:1598900
Molecular Function	GO:0042802	identical protein binding	Ahcy	IDA		Rat	PMID:2910349|RGD:1598902
Molecular Function	GO:0051287	NAD binding	Ahcy	IDA		Rat	PMID:2910349|RGD:1598902
Molecular Function	GO:0005515	protein binding	AHCY	IPI	UniProtKB:Q6AI12	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AHCY	IPI	UniProtKB:Q92624	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AHCY	IPI	UniProtKB:Q9BV19	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AHCY	IPI	UniProtKB:Q6AI12	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	AHCY	IPI	UniProtKB:Q9BV19	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	AHCY	IPI	UniProtKB:Q6AI12	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	AHCY	IPI	UniProtKB:Q9BV19	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	AHCY	IPI	UniProtKB:Q6AI12	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	AHCY	IPI	UniProtKB:Q9BV19	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	AHCY	IPI	UniProtKB:Q9BV19	Human	PMID:32296183
Cellular Component	GO:0005829	cytosol	AHCY	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Ahcy	IDA		Rat	PMID:7452268|RGD:1598904
Cellular Component	GO:0070062	extracellular exosome	AHCY	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	AHCY	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	AHCY	HDA		Human	PMID:23533145
Cellular Component	GO:0043005	neuron projection	Ahcy	IDA		Rat	PMID:7452268|RGD:1598904
Cellular Component	GO:0005634	nucleus	Ahcy	IDA		Rat	PMID:3518860|RGD:1598903
Biological Process	GO:0002439	chronic inflammatory response to antigenic stimulus	Ahcy	IMP		Rat	PMID:11123369|RGD:1598898
Biological Process	GO:0042745	circadian sleep/wake cycle	Ahcy	IDA		Rat	PMID:8330191|RGD:1598901
Biological Process	GO:0001666	response to hypoxia	Ahcy	IEP		Rat	PMID:10646513|RGD:1598899
Biological Process	GO:0007584	response to nutrient	Ahcy	IDA		Rat	PMID:11575573|RGD:1598897
Biological Process	GO:0019510	S-adenosylhomocysteine catabolic process	Ahcy	IDA		Rat	PMID:11741948|RGD:730275
Biological Process	GO:0033353	S-adenosylmethionine cycle	ahcy	IMP	ZFIN:ZDB-GENO-090428-1	Zfish	PMID:19201949

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern