Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AFF3
  • Mouse genes Aff3
  • Rat genes Aff3
  • Zfish genes aff3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aff3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Aff3	IMP		Mouse	PMID:25162227
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Aff3	IDA		Mouse	PMID:25162227
Molecular Function	GO:0003690	double-stranded DNA binding	Aff3	IDA		Mouse	PMID:25162227
Cellular Component	GO:0005829	cytosol	AFF3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	AFF3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	AFF3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	AFF3	IDA		Human	PMID:8555498
Cellular Component	GO:0005634	nucleus	Aff3	IDA		Mouse	MGI:MGI:78128|PMID:8555498
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	AFF3	IMP		Human	PMID:18616733
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	Aff3	IEP		Mouse	MGI:MGI:3819916|PMID:18616733
Biological Process	GO:0006355	regulation of DNA-templated transcription	Aff3	IMP		Mouse	PMID:25162227
Biological Process	GO:0006355	regulation of DNA-templated transcription	Aff3	IDA		Mouse	PMID:25162227
Biological Process	GO:0034612	response to tumor necrosis factor	AFF3	IMP		Human	PMID:20444755

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern