Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Afdn

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes AFDN
- Mouse genes Afdn
- Rat genes Afdn
- Zfish genes afdna
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Afdn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	AFDN	IDA		Human	PMID:16882694
Molecular Function	GO:0045296	cadherin binding	AFDN	HDA		Human	PMID:25468996
Molecular Function	GO:0050839	cell adhesion molecule binding	Afdn	IPI	UniProtKB:P32507	Mouse	MGI:MGI:3828417\|PMID:10225955
Molecular Function	GO:0030274	LIM domain binding	Afdn	IPI	RGD:1302984	Rat	PMID:15140894\|RGD:1303994
Molecular Function	GO:0005515	protein binding	AFDN	IPI	UniProtKB:P12931	Human	PMID:17491594
Molecular Function	GO:0005515	protein binding	AFDN	IPI	UniProtKB:Q9BX67	Human	PMID:19461049
Molecular Function	GO:0005515	protein binding	AFDN	IPI	UniProtKB:Q9Y3L3	Human	PMID:22891260
Molecular Function	GO:0005515	protein binding	AFDN	IPI	UniProtKB:Q16643	Human	PMID:23750010
Molecular Function	GO:0005515	protein binding	AFDN	IPI	UniProtKB:Q92692	Human	PMID:23750010
Molecular Function	GO:0005515	protein binding	AFDN	IPI	UniProtKB:Q07157	Human	PMID:23885123
Molecular Function	GO:0005515	protein binding	AFDN	IPI	UniProtKB:Q9UDY2	Human	PMID:23885123
Molecular Function	GO:0005515	protein binding	AFDN	IPI	UniProtKB:Q9Y624	Human	PMID:23885123
Molecular Function	GO:0005515	protein binding	AFDN	IPI	UniProtKB:P29317	Human	PMID:27815408
Molecular Function	GO:0005515	protein binding	AFDN	IPI	UniProtKB:O14672	Human	PMID:30463011
Molecular Function	GO:0005515	protein binding	Afdn	IPI	PR:Q8VC66	Mouse	PMID:22027834
Molecular Function	GO:0005515	protein binding	Afdn	IPI	PR:Q8VC66	Mouse	PMID:12446711
Molecular Function	GO:0005515	protein binding	Afdn	IPI	UniProtKB:P26231	Rat	PMID:10974003\|RGD:8553258
Molecular Function	GO:0005515	protein binding	Afdn	IPI	RGD:708490	Rat	PMID:12446711\|RGD:629551
Molecular Function	GO:0005515	protein binding	Afdn	IPI	UniProtKB:Q8VC66	Rat	PMID:12446711\|RGD:629551
Molecular Function	GO:0005515	protein binding	Afdn	IPI	UniProtKB:Q16643	Rat	PMID:23750010\|RGD:8553250
Molecular Function	GO:0005515	protein binding	Afdn	IPI	UniProtKB:Q3UIL6	Rat	PMID:23990464\|RGD:13792516
Molecular Function	GO:0031267	small GTPase binding	AFDN	IPI	UniProtKB:Q9Y3L5	Human	PMID:23885123
Cellular Component	GO:0005912	adherens junction	Afdn	IDA		Mouse	PMID:12203721
Cellular Component	GO:0005912	adherens junction	Afdn	IDA		Mouse	PMID:12515806
Cellular Component	GO:0005912	adherens junction	Afdn	IDA		Mouse	PMID:11731229
Cellular Component	GO:0005912	adherens junction	Afdn	IDA		Mouse	PMID:15728677
Cellular Component	GO:0005912	adherens junction	Afdn	IDA		Rat	PMID:9334353\|RGD:1299529
Cellular Component	GO:0043296	apical junction complex	Afdn	IDA		Mouse	PMID:22512338
Cellular Component	GO:0045177	apical part of cell	Afdn	IDA		Mouse	PMID:10704870
Cellular Component	GO:0030424	axon	Afdn	IDA		Rat	PMID:18181141\|RGD:2314668
Cellular Component	GO:0030054	cell junction	AFDN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030054	cell junction	Afdn	IDA		Mouse	PMID:15509704
Cellular Component	GO:0044291	cell-cell contact zone	AFDN	IDA		Human	PMID:16882694
Cellular Component	GO:0005911	cell-cell junction	AFDN	IDA		Human	PMID:19461049
Cellular Component	GO:0005911	cell-cell junction	Afdn	IDA		Mouse	MGI:MGI:5532791\|PMID:23990464
Cellular Component	GO:0005911	cell-cell junction	Afdn	IDA		Mouse	PMID:18604197
Cellular Component	GO:0005737	cytoplasm	Afdn	IDA		Mouse	PMID:22027834
Cellular Component	GO:0005737	cytoplasm	Afdn	IDA		Mouse	PMID:15509704
Cellular Component	GO:0005829	cytosol	AFDN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0060076	excitatory synapse	Afdn	IDA		Rat	PMID:22948147\|RGD:13838731
Cellular Component	GO:0016607	nuclear speck	AFDN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	AFDN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	AFDN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0046930	pore complex	AFDN	IMP		Human	PMID:30463011
Cellular Component	GO:0046930	pore complex	Afdn	IMP		Mouse	MGI:MGI:6316557\|PMID:30463011
Cellular Component	GO:0036477	somatodendritic compartment	Afdn	IDA		Rat	PMID:18181141\|RGD:2314668
Cellular Component	GO:0070160	tight junction	AFDN	IDA		Human	PMID:27815408
Biological Process	GO:0034334	adherens junction maintenance	Afdn	IMP		Mouse	PMID:25100583
Biological Process	GO:0070830	bicellular tight junction assembly	AFDN	IMP		Human	PMID:27815408
Biological Process	GO:0048854	brain morphogenesis	Afdn	IGI	MGI:MGI:95387	Mouse	PMID:25100583
Biological Process	GO:0044331	cell-cell adhesion mediated by cadherin	Afdn	IMP		Mouse	MGI:MGI:5532791\|PMID:23990464
Biological Process	GO:0021987	cerebral cortex development	Afdn	IMP	MGI:MGI:5607284	Mouse	PMID:25100583
Biological Process	GO:0021987	cerebral cortex development	Afdn	IGI	MGI:MGI:95387	Mouse	PMID:25100583
Biological Process	GO:0140059	dendrite arborization	Afdn	IMP		Rat	PMID:22948147\|RGD:13838731
Biological Process	GO:0090557	establishment of endothelial intestinal barrier	AFDN	IMP		Human	PMID:23885123
Biological Process	GO:0061951	establishment of protein localization to plasma membrane	Afdn	IMP		Mouse	MGI:MGI:5532791\|PMID:23990464
Biological Process	GO:0048872	homeostasis of number of cells	Afdn	IGI	MGI:MGI:95387	Mouse	PMID:25100583
Biological Process	GO:0030336	negative regulation of cell migration	AFDN	IMP		Human	PMID:21478912
Biological Process	GO:0060563	neuroepithelial cell differentiation	Afdn	IGI	MGI:MGI:95387	Mouse	PMID:25100583
Biological Process	GO:0046931	pore complex assembly	AFDN	IMP		Human	PMID:30463011
Biological Process	GO:0046931	pore complex assembly	Afdn	IMP		Mouse	MGI:MGI:6316557\|PMID:30463011
Biological Process	GO:0022409	positive regulation of cell-cell adhesion	AFDN	IMP		Human	PMID:25893857
Biological Process	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	AFDN	IMP		Human	PMID:16882694
Biological Process	GO:1903861	positive regulation of dendrite extension	Afdn	IMP		Rat	PMID:22948147\|RGD:13838731
Biological Process	GO:0050775	positive regulation of dendrite morphogenesis	Afdn	IMP		Rat	PMID:22948147\|RGD:13838731
Biological Process	GO:0061003	positive regulation of dendritic spine morphogenesis	Afdn	IMP		Rat	PMID:22948147\|RGD:13838731
Biological Process	GO:0010628	positive regulation of gene expression	AFDN	IMP		Human	PMID:25893857
Biological Process	GO:0043547	positive regulation of GTPase activity	AFDN	IMP		Human	PMID:23885123
Biological Process	GO:0061885	positive regulation of mini excitatory postsynaptic potential	Afdn	IMP		Rat	PMID:22948147\|RGD:13838731
Biological Process	GO:1902414	protein localization to cell junction	Afdn	IMP		Mouse	PMID:22512338
Biological Process	GO:0060019	radial glial cell differentiation	Afdn	IGI	MGI:MGI:95387	Mouse	PMID:25100583
Biological Process	GO:0070445	regulation of oligodendrocyte progenitor proliferation	Afdn	IGI	MGI:MGI:95387	Mouse	PMID:25100583
Biological Process	GO:0021537	telencephalon development	Afdn	IGI	MGI:MGI:95387	Mouse	PMID:25100583

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.