Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ADD3
  • Mouse genes Add3
  • Rat genes Add3
  • Zfish genes add3a,add3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Add3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Add3	IPI	RGD:2041	Rat	PMID:7592723|RGD:631726
Molecular Function	GO:0005080	protein kinase C binding	Add3	IDA		Rat	PMID:8442667|RGD:631733
Molecular Function	GO:0005200	structural constituent of cytoskeleton	Add3	IDA		Mouse	PMID:10485892
Cellular Component	GO:0005903	brush border	Add3	IDA		Mouse	MGI:MGI:5621262|PMID:22114352
Cellular Component	GO:0005938	cell cortex	Add3	IDA		Mouse	PMID:1864459
Cellular Component	GO:0005911	cell-cell junction	Add3	IDA		Mouse	PMID:1864459
Cellular Component	GO:0000794	condensed nuclear chromosome	Add3	IDA		Mouse	PMID:1864459
Cellular Component	GO:0005737	cytoplasm	Add3	IDA		Mouse	PMID:1864459
Cellular Component	GO:0005856	cytoskeleton	Add3	IDA		Mouse	PMID:10485892
Cellular Component	GO:0005856	cytoskeleton	Add3	IDA		Rat	PMID:7592723|RGD:631726
Cellular Component	GO:0016020	membrane	Add3	IDA		Mouse	PMID:10485892
Cellular Component	GO:0005886	plasma membrane	ADD3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0014069	postsynaptic density	Add3	IDA		Mouse	PMID:17114649
Biological Process	GO:0061008	hepaticobiliary system development	add3a	IMP	ZFIN:ZDB-GENO-170630-15	Zfish	PMID:27526058
Biological Process	GO:0051495	positive regulation of cytoskeleton organization	Add3	IMP		Rat	PMID:32029431|RGD:150340736
Biological Process	GO:0045907	positive regulation of vasoconstriction	Add3	IMP		Rat	PMID:27927653|RGD:13446409
Biological Process	GO:0009410	response to xenobiotic stimulus	Add3	IDA		Rat	PMID:10823823|RGD:2317718

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern