Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ADAM3A
  • Mouse genes Adam3
  • Rat genes Adam3a
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Adam3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Adam3	IPI	UniProtKB:Q9JMI7	Mouse	MGI:MGI:5492179|PMID:23633567
Molecular Function	GO:0005515	protein binding	Adam3	IPI	UniProtKB:Q3TTE0|UniProtKB:Q9JMI7	Mouse	MGI:MGI:5564881|PMID:23969891
Molecular Function	GO:0005515	protein binding	Adam3	IPI	PR:Q9DBX2	Mouse	PMID:22357757
Molecular Function	GO:0005515	protein binding	Adam3	IPI	PR:Q9CWP4	Mouse	PMID:24501175
Cellular Component	GO:0009986	cell surface	Adam3	IDA		Mouse	PMID:21339297
Cellular Component	GO:0009986	cell surface	Adam3	IDA		Mouse	PMID:24501175
Cellular Component	GO:0009986	cell surface	Adam3	IDA		Mouse	PMID:15194697
Cellular Component	GO:0009986	cell surface	Adam3	IDA		Mouse	PMID:22357757
Cellular Component	GO:0045121	membrane raft	Adam3	IDA		Mouse	PMID:15194697
Cellular Component	GO:0005886	plasma membrane	Adam3	IDA		Mouse	MGI:MGI:5908344|PMID:15514464
Cellular Component	GO:0032991	protein-containing complex	Adam3	IDA		Mouse	PMID:19129510
Cellular Component	GO:0061827	sperm head	Adam3	IDA		Mouse	MGI:MGI:5908344|PMID:15514464
Biological Process	GO:0007339	binding of sperm to zona pellucida	Adam3	IMP	MGI:MGI:2156167	Mouse	PMID:15194697
Biological Process	GO:0007339	binding of sperm to zona pellucida	Adam3	IMP	MGI:MGI:6358812	Mouse	PMID:32529245
Biological Process	GO:0007339	binding of sperm to zona pellucida	Adam3	IDA		Mouse	PMID:16330764
Biological Process	GO:0009566	fertilization	Adam3	IMP		Mouse	MGI:MGI:3840087|PMID:19339711
Biological Process	GO:0030317	flagellated sperm motility	Adam3	IMP		Mouse	MGI:MGI:3840087|PMID:19339711
Biological Process	GO:0008584	male gonad development	Adam3a	IEP		Rat	PMID:12815633|RGD:10047128
Biological Process	GO:0010628	positive regulation of gene expression	Adam3	IMP	MGI:MGI:2156167	Mouse	PMID:19129510
Biological Process	GO:0050684	regulation of mRNA processing	Adam3	IMP	MGI:MGI:2156167	Mouse	PMID:19129510
Biological Process	GO:0007338	single fertilization	Adam3	IGI	MGI:MGI:2684974	Mouse	PMID:22621904
Biological Process	GO:0007338	single fertilization	Adam3	IGI	MGI:MGI:107472	Mouse	PMID:22621904

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern