Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ACOD1
  • Mouse genes Acod1
  • Rat genes Acod1
  • Zfish genes acod1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Acod1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047613	aconitate decarboxylase activity	ACOD1	IDA		Human	PMID:23610393
Molecular Function	GO:0047613	aconitate decarboxylase activity	ACOD1	IDA		Human	PMID:31548418
Molecular Function	GO:0047613	aconitate decarboxylase activity	ACOD1	IDA		Human	PMID:35662396
Molecular Function	GO:0047613	aconitate decarboxylase activity	Acod1	IDA		Mouse	MGI:MGI:6367434|PMID:31548418
Molecular Function	GO:0047613	aconitate decarboxylase activity	Acod1	IDA		Mouse	MGI:MGI:5490395|PMID:23610393
Molecular Function	GO:0047613	aconitate decarboxylase activity	Acod1	IMP		Mouse	MGI:MGI:6357088|PMID:30635240
Molecular Function	GO:0042803	protein homodimerization activity	ACOD1	IDA		Human	PMID:31548418
Molecular Function	GO:0042803	protein homodimerization activity	Acod1	IDA		Mouse	MGI:MGI:6367434|PMID:31548418
Cellular Component	GO:0005739	mitochondrion	Acod1	IDA		Mouse	MGI:MGI:5489057|PMID:19014335
Biological Process	GO:0035458	cellular response to interferon-beta	Acod1	IDA		Mouse	MGI:MGI:5489057|PMID:19014335
Biological Process	GO:0071347	cellular response to interleukin-1	Acod1	IDA		Mouse	MGI:MGI:5489057|PMID:19014335
Biological Process	GO:0071222	cellular response to lipopolysaccharide	ACOD1	IDA		Human	PMID:23609450
Biological Process	GO:0071222	cellular response to lipopolysaccharide	ACOD1	IDA		Human	PMID:23610393
Biological Process	GO:0071222	cellular response to lipopolysaccharide	ACOD1	IDA		Human	PMID:35662396
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Acod1	IDA		Mouse	MGI:MGI:5490396|PMID:23609450
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Acod1	IDA		Mouse	MGI:MGI:5490395|PMID:23610393
Biological Process	GO:0071219	cellular response to molecule of bacterial origin	Acod1	IDA		Mouse	MGI:MGI:5489057|PMID:19014335
Biological Process	GO:0071393	cellular response to progesterone stimulus	Acod1	IDA		Mouse	MGI:MGI:5488888|PMID:14500577
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Acod1	IDA		Mouse	MGI:MGI:5489057|PMID:19014335
Biological Process	GO:0071346	cellular response to type II interferon	Acod1	IDA		Mouse	MGI:MGI:5489057|PMID:19014335
Biological Process	GO:0006952	defense response	ACOD1	IDA		Human	PMID:23610393
Biological Process	GO:0006952	defense response	Acod1	IDA		Mouse	MGI:MGI:5490395|PMID:23610393
Biological Process	GO:0042742	defense response to bacterium	acod1	IMP	ZFIN:ZDB-MRPHLNO-150806-3	Zfish	PMID:23931757
Biological Process	GO:0051607	defense response to virus	Acod1	IMP		Mouse	MGI:MGI:6357088|PMID:30635240
Biological Process	GO:0007566	embryo implantation	Acod1	IMP		Mouse	MGI:MGI:5488888|PMID:14500577
Biological Process	GO:0050728	negative regulation of inflammatory response	Acod1	IDA		Mouse	MGI:MGI:5490396|PMID:23609450
Biological Process	GO:0045824	negative regulation of innate immune response	Acod1	IDA		Mouse	MGI:MGI:5490396|PMID:23609450
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	Acod1	IMP		Mouse	MGI:MGI:5490396|PMID:23609450
Biological Process	GO:0034136	negative regulation of toll-like receptor 2 signaling pathway	Acod1	IMP		Mouse	MGI:MGI:5490396|PMID:23609450
Biological Process	GO:0034144	negative regulation of toll-like receptor 4 signaling pathway	Acod1	IDA		Mouse	MGI:MGI:5490396|PMID:23609450
Biological Process	GO:0032480	negative regulation of type I interferon production	Acod1	IMP		Mouse	MGI:MGI:5490396|PMID:23609450
Biological Process	GO:0002760	positive regulation of antimicrobial humoral response	ACOD1	IDA		Human	PMID:23610393
Biological Process	GO:0002760	positive regulation of antimicrobial humoral response	Acod1	IDA		Mouse	MGI:MGI:5490395|PMID:23610393
Biological Process	GO:2000379	positive regulation of reactive oxygen species metabolic process	Acod1	IDA		Mouse	MGI:MGI:5490396|PMID:23609450
Biological Process	GO:1903426	regulation of reactive oxygen species biosynthetic process	acod1	IMP	ZFIN:ZDB-MRPHLNO-150806-3	Zfish	PMID:23931757
Biological Process	GO:0009617	response to bacterium	Acod1	IEP		Mouse	PMID:23012479
Biological Process	GO:0032496	response to lipopolysaccharide	Acod1	IDA		Mouse	PMID:7721348
Biological Process	GO:0072573	tolerance induction to lipopolysaccharide	ACOD1	IDA		Human	PMID:23609450
Biological Process	GO:0072573	tolerance induction to lipopolysaccharide	Acod1	IDA		Mouse	MGI:MGI:5490396|PMID:23609450

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern