Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ACAA2
  • Mouse genes Acaa2
  • Rat genes Acaa2
  • Zfish genes acaa2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Acaa2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003985	acetyl-CoA C-acetyltransferase activity	ACAA2	IDA		Human	PMID:25478839
Molecular Function	GO:0003988	acetyl-CoA C-acyltransferase activity	ACAA2	IDA		Human	PMID:25478839
Molecular Function	GO:0003988	acetyl-CoA C-acyltransferase activity	Acaa2	IDA		Rat	PMID:11879205|RGD:2317624
Molecular Function	GO:0003988	acetyl-CoA C-acyltransferase activity	Acaa2	IDA		Rat	PMID:16476568|RGD:2317620
Molecular Function	GO:0047617	acyl-CoA hydrolase activity	ACAA2	IMP		Human	PMID:25478839
Molecular Function	GO:0047617	acyl-CoA hydrolase activity	Acaa2	IDA		Rat	PMID:16476568|RGD:2317620
Molecular Function	GO:0005515	protein binding	ACAA2	IPI	UniProtKB:Q12983	Human	PMID:18371312
Molecular Function	GO:0003723	RNA binding	ACAA2	HDA		Human	PMID:22658674
Cellular Component	GO:0005743	mitochondrial inner membrane	Acaa2	HDA		Mouse	PMID:12865426
Cellular Component	GO:0005759	mitochondrial matrix	Acaa2	IDA		Rat	PMID:16476568|RGD:2317620
Cellular Component	GO:0005739	mitochondrion	ACAA2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	ACAA2	IDA		Human	PMID:18371312
Cellular Component	GO:0005739	mitochondrion	Acaa2	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Acaa2	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Acaa2	IDA		Rat	PMID:11879205|RGD:2317624
Biological Process	GO:0006084	acetyl-CoA metabolic process	Acaa2	IDA		Rat	PMID:16476568|RGD:2317620
Biological Process	GO:0071456	cellular response to hypoxia	ACAA2	IDA		Human	PMID:18371312
Biological Process	GO:0006635	fatty acid beta-oxidation	Acaa2	IDA		Rat	PMID:11879205|RGD:2317624
Biological Process	GO:0001945	lymph vessel development	acaa2	IMP	ZFIN:ZDB-MRPHLNO-181102-4	Zfish	PMID:29730294
Biological Process	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process	ACAA2	IDA		Human	PMID:18371312
Biological Process	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	ACAA2	IDA		Human	PMID:18371312
Biological Process	GO:0031998	regulation of fatty acid beta-oxidation	acaa2	IMP	ZFIN:ZDB-MRPHLNO-181102-4	Zfish	PMID:29730294

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern