About   Help   FAQ
Take the Alliance for Genomic Resources User Survey
Acaa2 Gene Detail
Summary
  • Symbol
    Acaa2
  • Name
    acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)
  • Synonyms
    0610011L04Rik, D18Ertd240e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098623
    NCBI Gene: 52538
  • Gene Overview
    MyGene.info: ACAA2
Location & Maps
more
  • Sequence Map
    Chr18:74779212-74806207 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      26996 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 50.76 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    ACAA2, acetyl-CoA acyltransferase 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ACAA2, acetyl-CoA acyltransferase 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DSAEC
  • Links
    NCBI Gene ID: 10449
    neXtProt AC: NX_P42765

  • Chr Location
    18q21.1; chr18:49783504-49813881 (-)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    6
  • Gene trapped
    5
  • Transposon induced
    1
  • Genomic Mutations
    1 involving Acaa2
  • Incidental Mutations
    Mutagenetix , APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    240
  • Tissues
    131
  • cDNA Data
    362
  • Literature Summary
    4
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 52538 NCBI Gene Model | MGI Sequence Detail 26996 C57BL/6J ±  kb
transcript NM_177470 RefSeq | MGI Sequence Detail 1500 C57BL/6  
polypeptide Q8BWT1 UniProt | EBI | MGI Sequence Detail 397 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    211 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 364
    cDNA 362
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGI:1915593, MGI:2147202, MGI:2147205
References
more
  • Summaries
    All 36
    Developmental Gene Expression 4
    Gene Ontology 8
    Phenotypes 5
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:193325 Boj SF, et al., Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell. 2012 Dec 21;151(7):1595-607
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
09/20/2016
MGI 6.05 		The Jackson Laboratory