Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ABCD4
  • Mouse genes Abcd4
  • Rat genes Abcd4
  • Zfish genes abcd4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Abcd4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015420	ABC-type vitamin B12 transporter activity	ABCD4	EXP		Human	PMID:33845046
Molecular Function	GO:0015420	ABC-type vitamin B12 transporter activity	ABCD4	IDA		Human	PMID:33845046
Molecular Function	GO:0015420	ABC-type vitamin B12 transporter activity	ABCD4	IMP		Human	PMID:33845046
Molecular Function	GO:0042802	identical protein binding	ABCD4	IPI	UniProtKB:O14678	Human	PMID:27456980
Molecular Function	GO:0005515	protein binding	ABCD4	IPI	UniProtKB:Q9NUN5	Human	PMID:25535791
Molecular Function	GO:0005515	protein binding	ABCD4	IPI	UniProtKB:Q9Y4U1	Human	PMID:25535791
Molecular Function	GO:0005515	protein binding	ABCD4	IPI	UniProtKB:Q9NUN5	Human	PMID:27456980
Molecular Function	GO:0005515	protein binding	ABCD4	IPI	UniProtKB:Q9NUN5	Human	PMID:28572511
Molecular Function	GO:0005515	protein binding	ABCD4	IPI	UniProtKB:Q9NUN5	Human	PMID:33845046
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ABCD4	IDA		Human	PMID:27456980
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Abcd4	IDA		Mouse	MGI:MGI:5320280|PMID:19010322
Cellular Component	GO:0005765	lysosomal membrane	ABCD4	IDA		Human	PMID:33845046
Cellular Component	GO:0005765	lysosomal membrane	ABCD4	IDA		Human	PMID:27456980
Cellular Component	GO:0005777	peroxisome	ABCD4	IDA		Human	PMID:14533738
Cellular Component	GO:0005777	peroxisome	ABCD4	IDA		Human	PMID:9302272
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Abcd4	IEP		Mouse	PMID:20439489
Biological Process	GO:0009235	cobalamin metabolic process	ABCD4	IMP		Human	PMID:22922874
Biological Process	GO:0009235	cobalamin metabolic process	ABCD4	IDA		Human	PMID:33845046
Biological Process	GO:0015889	cobalamin transport	ABCD4	IMP		Human	PMID:33845046

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern