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Abcd4
Gene Detail
Symbol

Name
ID
Abcd4
ATP-binding cassette, sub-family D (ALD), member 4
MGI:1349217
Synonyms
P69r, Pxmp1l
Feature Type
protein coding gene
Genetic Map
Chromosome 12
39.30 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr12:84602531-84617466 bp, - strand
From Ensembl annotation of GRCm38

  14936 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3703  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Abcd4

Human
homologs
Human Homolog ABCD4, ATP-binding cassette, sub-family D (ALD), member 4
NCBI Gene ID 5826
neXtProt AC  NX_O14678
Human Synonyms  ABC41, EST352188, MAHCJ, P70R, P79R, PMP69, PXMP1L
Human Chr (Location)  14q24.3; chr14:74285277-74303064 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human ABCD4
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(4) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Abcd4 interacts with 59 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (5 records)
Data Summary: Results (137)    Tissues (109)    Images (19)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 113
Northern blot 24
cDNA source data(36)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(40) cDNA(40)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000021240 (Evidence)
Entrez Gene19300 (Evidence)
UniGene229109
DFCITC1584245, TC1587850
DoTSDT.99849132, DT.91311646, DT.60103270
NIA Mouse Gene IndexU034172
Consensus CDS ProjectCCDS26047.1
International Mouse Knockout Project StatusAbcd4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021240 Ensembl Gene Model | MGI Sequence Detail 14936 C57BL/6J ±  kb
transcript ENSMUST00000021666 Ensembl | MGI Sequence Detail 2527 Not Applicable 
polypeptide ENSMUSP00000021666 Ensembl | MGI Sequence Detail 606 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(15) UniProt(5)
Polymorphisms
SNPs within 2kb(87 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003593 AAA+ ATPase domain
InterPro IPR017871 ABC transporter, conserved site
InterPro IPR003439 ABC transporter-like
InterPro IPR010509 ABC transporter, N-terminal
InterPro IPR011527 ABC transporter, transmembrane domain, type 1
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000031253 ATP-binding cassette sub-family D member 4
References
(Earliest) J:49554 Holzinger A, et al., The mouse gene encoding the peroxisomal membrane protein 1-like protein (PXMP1-L): cDNA cloning, genomic organization and comparative expression studies. FEBS Lett. 1998 Aug 14;433(1-2):179-83
(Latest) J:196080 Elsen GE, et al., The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):4081-6
All references(35)
Other
accession IDs
MGI:1298215

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory