Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AACS
  • Mouse genes Aacs
  • Rat genes Aacs
  • Zfish genes aacs
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aacs

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030729	acetoacetate-CoA ligase activity	Aacs	IDA		Rat	PMID:3082367|RGD:2301027
Molecular Function	GO:0047760	butyrate-CoA ligase activity	Aacs	IDA		Rat	PMID:6539623|RGD:2326228
Molecular Function	GO:0005515	protein binding	AACS	IPI	UniProtKB:Q96DZ9	Human	PMID:25416956
Cellular Component	GO:0005829	cytosol	Aacs	IDA		Rat	PMID:17724028|RGD:2301019
Biological Process	GO:0060612	adipose tissue development	Aacs	IEP		Rat	PMID:16055091|RGD:2301021
Biological Process	GO:0071397	cellular response to cholesterol	Aacs	IEP		Rat	PMID:3663886|RGD:2326225
Biological Process	GO:0071333	cellular response to glucose stimulus	Aacs	IMP		Rat	PMID:17724028|RGD:2301019
Biological Process	GO:0071394	cellular response to testosterone stimulus	Aacs	IEP		Rat	PMID:19085696|RGD:2326193
Biological Process	GO:0001889	liver development	Aacs	IDA		Rat	PMID:10513626|RGD:2301023
Biological Process	GO:0032024	positive regulation of insulin secretion	Aacs	IMP		Rat	PMID:17724028|RGD:2301019
Biological Process	GO:0045471	response to ethanol	Aacs	IDA		Rat	PMID:8104400|RGD:2301024
Biological Process	GO:0007584	response to nutrient	Aacs	IDA		Rat	PMID:3082367|RGD:2301027
Biological Process	GO:0034201	response to oleic acid	Aacs	IDA		Rat	PMID:2565110|RGD:2301026
Biological Process	GO:0014070	response to organic cyclic compound	Aacs	IDA		Rat	PMID:3082367|RGD:2301027
Biological Process	GO:0010243	response to organonitrogen compound	Aacs	IDA		Rat	PMID:6501306|RGD:2301028
Biological Process	GO:0014074	response to purine-containing compound	Aacs	IEP		Rat	PMID:6501306|RGD:2301028
Biological Process	GO:0042594	response to starvation	Aacs	IEP		Rat	PMID:33671|RGD:2326230
Biological Process	GO:0009410	response to xenobiotic stimulus	Aacs	IDA		Rat	PMID:12034369|RGD:2301022
Biological Process	GO:0050872	white fat cell differentiation	Aacs	IEP		Rat	PMID:16055091|RGD:2301021

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern