Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes A1CF
  • Mouse genes A1cf
  • Rat genes A1cf
  • Zfish genes a1cf
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set A1cf

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140767	enzyme-substrate adaptor activity	A1CF	IDA		Human	PMID:11871661
Molecular Function	GO:0140767	enzyme-substrate adaptor activity	A1CF	IDA		Human	PMID:24916387
Molecular Function	GO:0003729	mRNA binding	A1cf	IDA		Rat	PMID:11870221|RGD:631910
Molecular Function	GO:0005515	protein binding	A1CF	IPI	UniProtKB:P41238	Human	PMID:10669759
Molecular Function	GO:0005515	protein binding	A1CF	IPI	UniProtKB:O14787	Human	PMID:12896982
Molecular Function	GO:0005515	protein binding	A1CF	IPI	UniProtKB:A0AV96	Human	PMID:24916387
Molecular Function	GO:0005515	protein binding	A1CF	IPI	UniProtKB:Q04864	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	A1CF	IPI	UniProtKB:Q13077	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	A1CF	IPI	UniProtKB:Q13643	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	A1CF	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	A1CF	IPI	UniProtKB:O43482	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	A1CF	IPI	UniProtKB:O76011	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	A1CF	IPI	UniProtKB:Q04637-9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	A1CF	IPI	UniProtKB:Q13077	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	A1CF	IPI	UniProtKB:Q14192	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	A1CF	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	A1CF	IPI	UniProtKB:Q16082	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	A1CF	IPI	UniProtKB:Q16610	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	A1CF	IPI	UniProtKB:Q58EX7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	A1CF	IPI	UniProtKB:Q5BKX5-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	A1CF	IPI	UniProtKB:Q7L591-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	A1CF	IPI	UniProtKB:Q7Z3K3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	A1CF	IPI	UniProtKB:Q8N6F8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	A1CF	IPI	UniProtKB:Q8NCR6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	A1CF	IPI	UniProtKB:Q96G42	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	A1CF	IPI	UniProtKB:Q9UFD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	A1cf	IPI	PR:Q91WT8	Mouse	PMID:24916387
Molecular Function	GO:0005515	protein binding	A1cf	IPI	UniProtKB:P38483	Rat	PMID:10781591|RGD:8553657
Molecular Function	GO:0005515	protein binding	A1cf	IPI	UniProtKB:Q99PF5	Rat	PMID:10781591|RGD:8553657
Molecular Function	GO:0003727	single-stranded RNA binding	A1CF	IDA		Human	PMID:11871661
Cellular Component	GO:0030895	apolipoprotein B mRNA editing enzyme complex	A1CF	IDA		Human	PMID:10781591
Cellular Component	GO:0030895	apolipoprotein B mRNA editing enzyme complex	A1CF	IDA		Human	PMID:24916387
Cellular Component	GO:0005737	cytoplasm	A1CF	IDA		Human	PMID:12881431
Cellular Component	GO:0005737	cytoplasm	A1cf	IDA		Mouse	PMID:20541607
Cellular Component	GO:0005737	cytoplasm	A1cf	IDA		Rat	PMID:11870221|RGD:631910
Cellular Component	GO:0000792	heterochromatin	A1cf	IDA		Rat	PMID:11870221|RGD:631910
Cellular Component	GO:0045293	mRNA editing complex	A1cf	IDA		Rat	PMID:16820530|RGD:9587738
Cellular Component	GO:0005654	nucleoplasm	A1CF	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	A1CF	IDA		Human	PMID:12881431
Cellular Component	GO:0005634	nucleus	A1CF	IDA		Human	PMID:24916387
Cellular Component	GO:0005634	nucleus	A1cf	IDA		Mouse	PMID:20541607
Biological Process	GO:0016554	cytidine to uridine editing	A1CF	IDA		Human	PMID:24916387
Biological Process	GO:0016554	cytidine to uridine editing	A1CF	IDA		Human	PMID:30844405
Biological Process	GO:0016554	cytidine to uridine editing	A1cf	IDA		Mouse	MGI:MGI:6331191|PMID:30309881
Biological Process	GO:0016554	cytidine to uridine editing	A1cf	IDA		Mouse	MGI:MGI:7387172|PMID:30844405
Biological Process	GO:0016554	cytidine to uridine editing	A1cf	IGI	MGI:MGI:103298	Mouse	PMID:24916387
Biological Process	GO:0016554	cytidine to uridine editing	A1cf	IMP		Rat	PMID:10669759|RGD:9587747
Biological Process	GO:0007566	embryo implantation	A1cf	IMP	MGI:MGI:3690371	Mouse	PMID:16055734
Biological Process	GO:0010609	mRNA localization resulting in post-transcriptional regulation of gene expression	A1cf	IGI	MGI:MGI:104663	Mouse	PMID:20541607
Biological Process	GO:0016556	mRNA modification	A1CF	IDA		Human	PMID:11134005
Biological Process	GO:0016556	mRNA modification	A1cf	IGI	MGI:MGI:104663	Mouse	PMID:20541607
Biological Process	GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	A1CF	IDA		Human	PMID:12881431
Biological Process	GO:0050714	positive regulation of protein secretion	A1cf	IMP		Rat	PMID:20541607|RGD:13831121
Biological Process	GO:0050821	protein stabilization	A1CF	IDA		Human	PMID:12881431

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern