| GO term: | mRNA modification |
| Synonym: | mRNA editing |
| GO id: | GO:0016556 |
| Definition: | The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically. |
| Comments | The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing. Parallel changes were made for substrate (e.g. tRNA, rRNA, etc.) specific child terms of 'RNA editing'. |
| Number of paths to term: | 27 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
biological_processcellular processcellular metabolic processcellular aromatic compound metabolic processnucleobase-containing compound metabolic processnucleic acid metabolic processRNA metabolic processmRNA metabolic processhistone mRNA metabolic process +mRNA catabolic process +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +mRNA processing +biological_processcellular processcellular metabolic processcellular aromatic compound metabolic processnucleobase-containing compound metabolic processnucleic acid metabolic processRNA metabolic processRNA modificationbase conversion or substitution editing +chloroplast RNA modification +mitochondrial RNA modification +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +oxidative RNA demethylation +pseudouridine synthesis +RNA methylation +RNA nucleotide deletion +RNA nucleotide insertion +rRNA modification +snRNA modification +tRNA modification +biological_processcellular processcellular metabolic processcellular macromolecule metabolic processRNA metabolic processmRNA metabolic processhistone mRNA metabolic process +mRNA catabolic process +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +mRNA processing +biological_processcellular processcellular metabolic processcellular macromolecule metabolic processRNA metabolic processRNA modificationbase conversion or substitution editing +chloroplast RNA modification +mitochondrial RNA modification +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +oxidative RNA demethylation +pseudouridine synthesis +RNA methylation +RNA nucleotide deletion +RNA nucleotide insertion +rRNA modification +snRNA modification +tRNA modification +biological_processcellular processcellular metabolic processcellular nitrogen compound metabolic processnucleobase-containing compound metabolic processnucleic acid metabolic processRNA metabolic processmRNA metabolic processhistone mRNA metabolic process +mRNA catabolic process +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +mRNA processing +biological_processcellular processcellular metabolic processcellular nitrogen compound metabolic processnucleobase-containing compound metabolic processnucleic acid metabolic processRNA metabolic processRNA modificationbase conversion or substitution editing +chloroplast RNA modification +mitochondrial RNA modification +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +oxidative RNA demethylation +pseudouridine synthesis +RNA methylation +RNA nucleotide deletion +RNA nucleotide insertion +rRNA modification +snRNA modification +tRNA modification +biological_processcellular processcellular metabolic processheterocycle metabolic processnucleobase-containing compound metabolic processnucleic acid metabolic processRNA metabolic processmRNA metabolic processhistone mRNA metabolic process +mRNA catabolic process +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +mRNA processing +biological_processcellular processcellular metabolic processheterocycle metabolic processnucleobase-containing compound metabolic processnucleic acid metabolic processRNA metabolic processRNA modificationbase conversion or substitution editing +chloroplast RNA modification +mitochondrial RNA modification +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +oxidative RNA demethylation +pseudouridine synthesis +RNA methylation +RNA nucleotide deletion +RNA nucleotide insertion +rRNA modification +snRNA modification +tRNA modification +biological_processmetabolic processcellular metabolic processcellular aromatic compound metabolic processnucleobase-containing compound metabolic processnucleic acid metabolic processRNA metabolic processmRNA metabolic processhistone mRNA metabolic process +mRNA catabolic process +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +mRNA processing +biological_processmetabolic processcellular metabolic processcellular aromatic compound metabolic processnucleobase-containing compound metabolic processnucleic acid metabolic processRNA metabolic processRNA modificationbase conversion or substitution editing +chloroplast RNA modification +mitochondrial RNA modification +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +oxidative RNA demethylation +pseudouridine synthesis +RNA methylation +RNA nucleotide deletion +RNA nucleotide insertion +rRNA modification +snRNA modification +tRNA modification +biological_processmetabolic processcellular metabolic processcellular macromolecule metabolic processRNA metabolic processmRNA metabolic processhistone mRNA metabolic process +mRNA catabolic process +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +mRNA processing +biological_processmetabolic processcellular metabolic processcellular macromolecule metabolic processRNA metabolic processRNA modificationbase conversion or substitution editing +chloroplast RNA modification +mitochondrial RNA modification +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +oxidative RNA demethylation +pseudouridine synthesis +RNA methylation +RNA nucleotide deletion +RNA nucleotide insertion +rRNA modification +snRNA modification +tRNA modification +biological_processmetabolic processcellular metabolic processcellular nitrogen compound metabolic processnucleobase-containing compound metabolic processnucleic acid metabolic processRNA metabolic processmRNA metabolic processhistone mRNA metabolic process +mRNA catabolic process +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +mRNA processing +biological_processmetabolic processcellular metabolic processcellular nitrogen compound metabolic processnucleobase-containing compound metabolic processnucleic acid metabolic processRNA metabolic processRNA modificationbase conversion or substitution editing +chloroplast RNA modification +mitochondrial RNA modification +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +oxidative RNA demethylation +pseudouridine synthesis +RNA methylation +RNA nucleotide deletion +RNA nucleotide insertion +rRNA modification +snRNA modification +tRNA modification +biological_processmetabolic processcellular metabolic processheterocycle metabolic processnucleobase-containing compound metabolic processnucleic acid metabolic processRNA metabolic processmRNA metabolic processhistone mRNA metabolic process +mRNA catabolic process +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +mRNA processing +biological_processmetabolic processcellular metabolic processheterocycle metabolic processnucleobase-containing compound metabolic processnucleic acid metabolic processRNA metabolic processRNA modificationbase conversion or substitution editing +chloroplast RNA modification +mitochondrial RNA modification +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +oxidative RNA demethylation +pseudouridine synthesis +RNA methylation +RNA nucleotide deletion +RNA nucleotide insertion +rRNA modification +snRNA modification +tRNA modification +biological_processmetabolic processnitrogen compound metabolic processcellular nitrogen compound metabolic processnucleobase-containing compound metabolic processnucleic acid metabolic processRNA metabolic processmRNA metabolic processhistone mRNA metabolic process +mRNA catabolic process +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +mRNA processing +biological_processmetabolic processnitrogen compound metabolic processcellular nitrogen compound metabolic processnucleobase-containing compound metabolic processnucleic acid metabolic processRNA metabolic processRNA modificationbase conversion or substitution editing +chloroplast RNA modification +mitochondrial RNA modification +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +oxidative RNA demethylation +pseudouridine synthesis +RNA methylation +RNA nucleotide deletion +RNA nucleotide insertion +rRNA modification +snRNA modification +tRNA modification +biological_processmetabolic processorganic substance metabolic processmacromolecule metabolic processcellular macromolecule metabolic processRNA metabolic processmRNA metabolic processhistone mRNA metabolic process +mRNA catabolic process +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +mRNA processing +biological_processmetabolic processorganic substance metabolic processmacromolecule metabolic processcellular macromolecule metabolic processRNA metabolic processRNA modificationbase conversion or substitution editing +chloroplast RNA modification +mitochondrial RNA modification +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +oxidative RNA demethylation +pseudouridine synthesis +RNA methylation +RNA nucleotide deletion +RNA nucleotide insertion +rRNA modification +snRNA modification +tRNA modification +biological_processmetabolic processorganic substance metabolic processmacromolecule metabolic processmacromolecule modificationRNA modificationbase conversion or substitution editing +chloroplast RNA modification +mitochondrial RNA modification +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +oxidative RNA demethylation +pseudouridine synthesis +RNA methylation +RNA nucleotide deletion +RNA nucleotide insertion +rRNA modification +snRNA modification +tRNA modification +biological_processmetabolic processorganic substance metabolic processmacromolecule metabolic processnucleic acid metabolic processRNA metabolic processmRNA metabolic processhistone mRNA metabolic process +mRNA catabolic process +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +mRNA processing +biological_processmetabolic processorganic substance metabolic processmacromolecule metabolic processnucleic acid metabolic processRNA metabolic processRNA modificationbase conversion or substitution editing +chloroplast RNA modification +mitochondrial RNA modification +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +oxidative RNA demethylation +pseudouridine synthesis +RNA methylation +RNA nucleotide deletion +RNA nucleotide insertion +rRNA modification +snRNA modification +tRNA modification +biological_processmetabolic processorganic substance metabolic processorganic cyclic compound metabolic processnucleobase-containing compound metabolic processnucleic acid metabolic processRNA metabolic processmRNA metabolic processhistone mRNA metabolic process +mRNA catabolic process +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +mRNA processing +biological_processmetabolic processorganic substance metabolic processorganic cyclic compound metabolic processnucleobase-containing compound metabolic processnucleic acid metabolic processRNA metabolic processRNA modificationbase conversion or substitution editing +chloroplast RNA modification +mitochondrial RNA modification +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +oxidative RNA demethylation +pseudouridine synthesis +RNA methylation +RNA nucleotide deletion +RNA nucleotide insertion +rRNA modification +snRNA modification +tRNA modification +biological_processmetabolic processprimary metabolic processnucleobase-containing compound metabolic processnucleic acid metabolic processRNA metabolic processmRNA metabolic processhistone mRNA metabolic process +mRNA catabolic process +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +mRNA processing +biological_processmetabolic processprimary metabolic processnucleobase-containing compound metabolic processnucleic acid metabolic processRNA metabolic processRNA modificationbase conversion or substitution editing +chloroplast RNA modification +mitochondrial RNA modification +mRNA modification [GO:0016556] (9 genes, 12 annotations)chloroplast mRNA modificationmitochondrial mRNA modificationmRNA methylation +negative regulation of mRNA modificationpositive regulation of mRNA modificationregulation of mRNA modification +oxidative RNA demethylation +pseudouridine synthesis +RNA methylation +RNA nucleotide deletion +RNA nucleotide insertion +rRNA modification +snRNA modification +tRNA modification +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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