Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables cell adhesion molecule binding activity; metal ion binding activity; and metallopeptidase activity. Involved in several processes, including positive regulation of defense response; positive regulation of intracellular signal transduction; and positive regulation of leukocyte migration. Acts upstream of or within cell-cell adhesion. Located in plasma membrane. Part of alpha9-beta1 integrin-ADAM8 complex. Is expressed in several structures, including alimentary system; hindlimb cartilage condensation; reproductive system; respiratory system; and venous system. Orthologous to human ADAM8 (ADAM metallopeptidase domain 8).