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All mouse models of lipodystrophy with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | congenital generalized lipodystrophy type 1 | \Agpat2tm1Garg/\Agpat2tm1Garg | involves: 129S6/SvEvTac | J:146649 | View | |||
| congenital generalized lipodystrophy type 2 | \Bscl2tm1.1Lchan/\Bscl2tm1.1Lchan | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:211142 | View | ||||
| congenital generalized lipodystrophy type 2 | \Bscl2tm1.2Gliu/\Bscl2tm1.2Gliu | involves: 129 * 129S4/SvJaeSor * C57BL/6 * FVB/N | J:173404, J:211072 | View | ||||
| congenital generalized lipodystrophy type 2 | \Bscl2tm1Geno/\Bscl2tm1Geno | B6.129P2-Bscl2tm1Geno | J:200947 | View | ||||
| congenital generalized lipodystrophy type 4 | \Cavin1tm1Pfp/\Cavin1tm1Pfp | involves: 129S6/SvEvTac * C57BL/6 | J:150419 | View | ||||
| | congenital generalized lipodystrophy type 2 | \Ppargtm2(tTA)Yba/\Pparg+ | involves: 129S1/SvImJ * C57BL/6 | J:125992 | View | |||
| congenital generalized lipodystrophy type 2 | \Ppargtm3(tTA)Yba/\Pparg+ | involves: 129S1/SvImJ * C57BL/6 | J:125992 | View | ||||
| familial partial lipodystrophy |
\Lepob/\Lepob \Ppargtm1Avp/\Pparg+ |
involves: 129S2/SvPas * C57BL/6 | J:116568 | View | ||||
| familial partial lipodystrophy | \Ppargtm2(tTA)Yba/\Pparg+ | involves: 129S1/SvImJ * C57BL/6 | J:125992 | View | ||||
| familial partial lipodystrophy | \Ppargtm3(tTA)Yba/\Pparg+ | involves: 129S1/SvImJ * C57BL/6 | J:125992 | View | ||||
| familial partial lipodystrophy | \Zmpste24tm1Otin/\Zmpste24tm1Otin | involves: 129P2/Ola * C57BL/6 | J:76209 | View | ||||
| lipodystrophy |
\Atp6v0d1em1Nju/\Atp6v0d1em1Nju \Tg(Adipoq-cre)1Evdr/0 |
involves: FVB/NJ | J:346448 | View | ||||
| lipodystrophy | \Ebf1tm1Rug/\Ebf1tm1Rug | involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 | J:147179 | View | ||||
| lipodystrophy | \Lpin1fld-2J/\Lpin1fld-2J | C3H/HeJ-Lpin1fld-2J/J | J:66739 | View | ||||
| lipodystrophy |
\Mipeptm1.1Yhig/\Mipeptm1.1Yhig \Tg(Adipoq-cre)1Evdr/0 |
involves: C57BL/6J * C57BL/6N * FVB/NJ | J:365489 | View | ||||
| Transgenes and Other Mutations | congenital generalized lipodystrophy type 2 | \Tg(aP2-SREBF1c)9884Reh/0 | involves: C57BL/6J * SJL | J:50770 | View | |||
| familial partial lipodystrophy | \Tg(Fabp4-LMNA*R482Q)11ACdl/0 | FVB-Tg(Fabp4-LMNA*R482Q)11ACdl | J:149858 | View | ||||
| familial partial lipodystrophy | \Tg(Fabp4-LMNA*R482Q)17CCdl/0 | FVB/N-Tg(Fabp4-LMNA*R482Q)17CCdl | J:149858 | View | ||||
| lipodystrophy | \Tg(Fabp4-SREBF1)#Dajl/0 | involves: FVB | J:189510 | View | ||||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | familial partial lipodystrophy | \Lmnatm1Stw/\Lmna+ | involves: 129S1/Sv * C57BL/6J | J:75101 | View | |||
| familial partial lipodystrophy | \Lmnatm1Stw/\Lmnatm1Stw | involves: 129S1/Sv * C57BL/6J | J:75101 | View | ||||
| familial partial lipodystrophy | \Ppargtm1Avp/\Pparg+ | involves: 129S2/SvPas * C57BL/6 | J:116568 | View | ||||
| familial partial lipodystrophy | \Ppargtm1Mae/\Pparg+ | involves: 129S6/SvEvTac * C57BL/6 | J:91362 | View | ||||
| familial partial lipodystrophy | \Ppargtm1Rev/\Pparg+ | involves: 129S4/SvJae * C57BL/6J | J:60354 | View | ||||