Atp6v0d1^em1Nju
Endonuclease-mediated Allele Detail

Summary

• Symbol: Atp6v0d1^em1Nju
• Name: ATPase, H+ transporting, lysosomal V0 subunit D1; endonuclease-mediated mutation 1, Model Animal Research Center of Nanjing University
• MGI ID: MGI:7616526
• Synonyms: Atp6v0d1^flox
• Gene: Atp6v0d1 Location: Chr8:106251097-106292679 bp, - strand Genetic Position: Chr8, 53.04 cM
• Alliance: Atp6v0d1^em1Nju page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 2 was flanked by loxP sites via CRISPR/Cas9 technology. (J:346448)

Disease models

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atp6v0d1 Mutation: 19 strains or lines available

References

• Original: J:346448 Yuan W, et al., Myocardin reverses insulin resistance and ameliorates cardiomyopathy by increasing IRS-1 expression in a murine model of lipodystrophy caused by adipose deficiency of vacuolar H(+)-ATPase V0d1 subunit. Theranostics. 2024;14(5):2246-2264
• All: 1 reference(s)