Excel File Text File *Disease is associated/modeled with this Gene or a homolog. More...
      Disease Term Human Homologs Mouse Homologs Mouse Models Homology Source
     amyotrophic lateral sclerosis type 1 SOD1* Sod1* 39 models Alliance of Genome Resources
amyotrophic lateral sclerosis type 10 TARDBP* Tardbp* 24 models Alliance of Genome Resources
amyotrophic lateral sclerosis type 21 MATR3* Matr3* 1 model Alliance of Genome Resources
amyotrophic lateral sclerosis type 4 SETX* Setx* 2 models Alliance of Genome Resources
amyotrophic lateral sclerosis type 6 FUS* Fus* 6 models Alliance of Genome Resources
     amyotrophic lateral sclerosis ZNF106 Zfp106* 1 model Alliance of Genome Resources
amyotrophic lateral sclerosis PSMC4 Psmc4* 1 model Alliance of Genome Resources
amyotrophic lateral sclerosis EPG5 Epg5* 1 model Alliance of Genome Resources
amyotrophic lateral sclerosis ADARB1 Adarb1* 1 model Alliance of Genome Resources
amyotrophic lateral sclerosis type 1 VPS54 Vps54* 1 model Alliance of Genome Resources
amyotrophic lateral sclerosis type 1 VEGFA Vegfa* 1 model Alliance of Genome Resources
amyotrophic lateral sclerosis type 1 SOD2 Sod2* 1 model Alliance of Genome Resources
amyotrophic lateral sclerosis type 1 SNCG Sncg* 1 model Alliance of Genome Resources
     amyotrophic lateral sclerosis OPTN* Optn   Alliance of Genome Resources
amyotrophic lateral sclerosis PON2* Pon2   Alliance of Genome Resources
amyotrophic lateral sclerosis PON3* Pon3   Alliance of Genome Resources
amyotrophic lateral sclerosis PPARGC1A* Ppargc1a   Alliance of Genome Resources
amyotrophic lateral sclerosis SLC11A2* Slc11a2   Alliance of Genome Resources
amyotrophic lateral sclerosis SOD1* Sod1   Alliance of Genome Resources
amyotrophic lateral sclerosis TARDBP* Tardbp   Alliance of Genome Resources
amyotrophic lateral sclerosis TFAM* Tfam   Alliance of Genome Resources
amyotrophic lateral sclerosis TXNRD1* Txnrd1   Alliance of Genome Resources
amyotrophic lateral sclerosis UBQLN2* Ubqln2   Alliance of Genome Resources
amyotrophic lateral sclerosis UNC13A* Unc13a   Alliance of Genome Resources
amyotrophic lateral sclerosis VAPB* Vapb   Alliance of Genome Resources
amyotrophic lateral sclerosis VDR* Vdr   Alliance of Genome Resources
amyotrophic lateral sclerosis ALS2* Als2   Alliance of Genome Resources
amyotrophic lateral sclerosis ANG* Ang, Ang2, Ang3, Ang4, Ang5, Ang6   Alliance of Genome Resources
amyotrophic lateral sclerosis AOX1* Aox1   Alliance of Genome Resources
amyotrophic lateral sclerosis APOE* Apoe   Alliance of Genome Resources
amyotrophic lateral sclerosis CCNF* Ccnf   Alliance of Genome Resources
amyotrophic lateral sclerosis CCS* Ccs   Alliance of Genome Resources
amyotrophic lateral sclerosis CHMP2B* Chmp2b   Alliance of Genome Resources
amyotrophic lateral sclerosis CYLD* Cyld   Alliance of Genome Resources
amyotrophic lateral sclerosis DPP6* Dpp6   Alliance of Genome Resources
amyotrophic lateral sclerosis FUS* Fus   Alliance of Genome Resources
amyotrophic lateral sclerosis GOT1* Got1   Alliance of Genome Resources
amyotrophic lateral sclerosis GRN* Grn   Alliance of Genome Resources
amyotrophic lateral sclerosis GSK3A* Gsk3a   Alliance of Genome Resources
amyotrophic lateral sclerosis GSK3B* Gsk3b   Alliance of Genome Resources
amyotrophic lateral sclerosis HMGB1* Hmgb1   Alliance of Genome Resources
amyotrophic lateral sclerosis ITPR2* Itpr2   Alliance of Genome Resources
amyotrophic lateral sclerosis KIF5A* Kif5a   Alliance of Genome Resources
amyotrophic lateral sclerosis MTHFR* Mthfr   Alliance of Genome Resources
amyotrophic lateral sclerosis NEFH* Nefh   Alliance of Genome Resources
amyotrophic lateral sclerosis NEFL* Nefl   Alliance of Genome Resources
amyotrophic lateral sclerosis NEK1* Nek1   Alliance of Genome Resources
amyotrophic lateral sclerosis type 1 DCTN1* Dctn1 1 model Alliance of Genome Resources
amyotrophic lateral sclerosis type 1 NEFH* Nefh 4 models Alliance of Genome Resources
amyotrophic lateral sclerosis type 1 PRPH* Prph   Alliance of Genome Resources
amyotrophic lateral sclerosis type 11 FIG4* Fig4   Alliance of Genome Resources
amyotrophic lateral sclerosis type 12 OPTN* Optn   Alliance of Genome Resources
amyotrophic lateral sclerosis type 14 VCP* Vcp   Alliance of Genome Resources
amyotrophic lateral sclerosis type 15 UBQLN2* Ubqln2 2 models Alliance of Genome Resources
amyotrophic lateral sclerosis type 16 SIGMAR1* Sigmar1   Alliance of Genome Resources
amyotrophic lateral sclerosis type 18 PFN1* Pfn1 2 models Alliance of Genome Resources
amyotrophic lateral sclerosis type 19 ERBB4* Erbb4   Alliance of Genome Resources
amyotrophic lateral sclerosis type 2 ALS2* Als2 3 "NOT" models Alliance of Genome Resources
amyotrophic lateral sclerosis type 20 HNRNPA1*, HNRNPA1L2 Hnrnpa1, Hnrnpa1l2-ps2   Alliance of Genome Resources
amyotrophic lateral sclerosis type 22 TUBA4A* Tuba4a   Alliance of Genome Resources
amyotrophic lateral sclerosis type 23 ANXA11* Anxa11   Alliance of Genome Resources
amyotrophic lateral sclerosis type 5 SPG11* Spg11   Alliance of Genome Resources
amyotrophic lateral sclerosis type 8 VAPB* Vapb 1 model Alliance of Genome Resources
amyotrophic lateral sclerosis type 9 ANG* Ang, Ang2, Ang3, Ang4, Ang5, Ang6   Alliance of Genome Resources
frontotemporal dementia and/or amyotrophic lateral sclerosis-1 C9orf72* C9orf72 1 model Alliance of Genome Resources
frontotemporal dementia and/or amyotrophic lateral sclerosis-2 CHCHD10* Chchd10   Alliance of Genome Resources
frontotemporal dementia and/or amyotrophic lateral sclerosis-3 SQSTM1* Sqstm1   Alliance of Genome Resources
frontotemporal dementia and/or amyotrophic lateral sclerosis-4 TBK1* Tbk1   Alliance of Genome Resources

 
Transgenes and other genome features developed in mice to model this disease.
     Disease Term Transgenes and Other Genome Features Mouse Models
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G93A)2Gur 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G93A)dl1Gur 2 models
  amyotrophic lateral sclerosis type 1 Tg(SOD1*H46R)#Maw 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G127X)716Mrkl 1 model
  amyotrophic lateral sclerosis type 1 Tg(Thy1-SOD1*G93A)T3Hgrd 2 models
  amyotrophic lateral sclerosis type 1 Tg(Thy1-Sncg)HvP36Putt 1 model
  amyotrophic lateral sclerosis type 1 Tg(Thy1-DCTN1*G59S)M2Pcw 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*L126Z)#Deng 2 models
  amyotrophic lateral sclerosis type 1 Tg(SOD1*L126Z)45Dbo 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*H46R*H48Q)139Dbo 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*H46R*H48Q)58Dbo 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*H46R)LAra 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*H46R)IAra 1 model
  amyotrophic lateral sclerosis type 1 Tg(Myl1-SOD1*G93A)#Amu 1 model
  amyotrophic lateral sclerosis type 1 Tg(NEFH)200Jpj 2 models
  amyotrophic lateral sclerosis type 1 Tg(NFH)120Jpj 2 models
  amyotrophic lateral sclerosis type 1 Tg(Prnp-Immt/SOD1*G93A)7Gmnf 1 model
  amyotrophic lateral sclerosis type 1 Tg(Prnp-SOD1*G37R,-PSEN1)110Dbo 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*)125Dbo 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*)D-14Dbo 2 models
  amyotrophic lateral sclerosis type 1 Tg(SOD1*)DF7Yaw 2 models
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G37R)1Dwc 2 models
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G37R)9Dpr 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G37R)29Dpr 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G37R)42Dpr 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G37R)106Dpr 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G85R)74Dwc 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G85R)148Dwc 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G85R)#Roos 2 models
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G85R/EYFP)641Alho 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G85R/EYFP)737Alho 1 model
  amyotrophic lateral sclerosis type 1 Tg(Sod1*G86R)M1Jwg 1 model
  amyotrophic lateral sclerosis type 1 Tg(SOD1*G93A)1Gur 6 models
  amyotrophic lateral sclerosis type 10 Tg(CAG-dsRed2/RNAi:Tardbp)6Zxu 1 model
  amyotrophic lateral sclerosis type 10 Tg(Prnp-TARDBP)3cPtrc 1 model
  amyotrophic lateral sclerosis type 10 Tg(Prnp-TARDBP)4Jlel 1 model
  amyotrophic lateral sclerosis type 10 Tg(Prnp-TARDBP*A315T)23Jlel 1 model
  amyotrophic lateral sclerosis type 10 Tg(Prnp-TARDBP*A315T)95Balo 1 model
  amyotrophic lateral sclerosis type 10 Tg(Prnp-TARDBP*Q331K)103Dwc 1 model
  amyotrophic lateral sclerosis type 10 Tg(TARDBP)#Jpj 1 model
  amyotrophic lateral sclerosis type 10 Tg(TARDBP*A315T)#Jpj 1 model
  amyotrophic lateral sclerosis type 10 Tg(TARDBP*G348C)#Jpj 1 model
  amyotrophic lateral sclerosis type 10 Tg(tetO-TARDBP)12Vle 1 model
  amyotrophic lateral sclerosis type 10 Tg(tetO-TARDBP*)4Vle 2 models
  amyotrophic lateral sclerosis type 10 Tg(tetO-TARDBP*A315T)13Lmit 1 model
  amyotrophic lateral sclerosis type 10 Tg(Thy1-TARDBP)4Singh 2 models
  amyotrophic lateral sclerosis type 10 Tg(Thy1-TARDBP)6Singh 1 model
  amyotrophic lateral sclerosis type 10 Tg(Thy1-TARDBP*)BOddo 1 model
  amyotrophic lateral sclerosis type 15 Tg(Thy1-UBQLN2*P497S)3Mont 1 model
  amyotrophic lateral sclerosis type 15 Tg(Thy1-UBQLN2*P506T)6Mont 1 model
  amyotrophic lateral sclerosis type 4 Tg(Prnp-SETX*R2136H)1920Als 1 model
  amyotrophic lateral sclerosis type 6 Tg(Thy1-FUS*)1Dit 1 model
  amyotrophic lateral sclerosis type 6 Tg(CAG-lacZ,-FUS*R521G,-EGFP)682Gyu 1 model
  amyotrophic lateral sclerosis type 6 Tg(CAG-lacZ,-FUS,-EGFP)629Gyu 1 model
  amyotrophic lateral sclerosis type 6 Tg(Prnp-FUS)WT3Cshw 1 model
  amyotrophic lateral sclerosis type 6 Tg(Prnp-FUS*R521C)3313Ejh 1 model
  amyotrophic lateral sclerosis type 6 Tg(Thy1-FUS*)19Vlb 1 model
  amyotrophic lateral sclerosis type 8 Tg(Thy1-VAPB*P56S,-EGFP)D3Cai 1 model
  frontotemporal dementia and/or amyotrophic lateral sclerosis-1 Tg(C9orf72)500Lpwr 1 model