tetralogy of Fallot Disease Ontology Browser

Disease Ontology Browser

tetralogy of Fallot (DOID:6419)
Alliance: disease page
Synonyms: Ventricular septal defect with pulmonary stenosis or atresia, dextraposition of aorta, and hypertrophy of right ventricle
Alt IDs: OMIM:187500, ICD10CM:Q21.3, ICD9CM:745.2, MESH:D013771, NCI:C84505, UMLS_CUI:C0039685

Term Browser
Genes (27)
Models (17)

Disease References using Mouse Models (15)

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Gja5

Allelic Composition	Genetic Background	Reference	Phenotypes
\Gja5tm1Paul/\Gja5tm1Paul	involves: 129S4/SvJae * C57BL/6	J:109301	View
\Gja5tm1Paul/\Gja5+	involves: 129S4/SvJae * C57BL/6	J:109301	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Nkx2-5

Allelic Composition	Genetic Background	Reference	Phenotypes
\Nkx2-5tm2.1Mwc/\Nkx2-5+	B6J.Cg-Nkx2-5^tm2.1Mwc/Mwc	J:239808	View
\Nkx2-5tm3.1Mwc/\Nkx2-5+	B6J.Cg-Nkx2-5^tm3.1Mwc/Mwc	J:239808	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Zfpm2

Allelic Composition	Genetic Background	Reference	Phenotypes
\Zfpm2tm1Sho/\Zfpm2tm1Sho	involves: 129S1/Sv	J:62879, J:78688	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Bmp10

Allelic Composition	Genetic Background	Reference	Phenotypes
\Bmp10b2b2711Clo/\Bmp10b2b2711Clo	C57BL/6J-Bmp10^b2b2711Clo	J:175213	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Cited2

Allelic Composition	Genetic Background	Reference	Phenotypes
\Cited2tm1Ycy/\Cited2tm1Ycy	involves: C57BL/6J	J:78364	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Dnah5

Allelic Composition	Genetic Background	Reference	Phenotypes
\Dnah5hlb612/\Dnah5hlb612	involves: C57BL/6J	J:130755	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Dock1

Allelic Composition	Genetic Background	Reference	Phenotypes
\Dock1b2b3190Clo/\Dock1b2b3190Clo	C57BL/6J-Dock1^b2b3190Clo	J:175213	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Fgf8

Allelic Composition	Genetic Background	Reference	Phenotypes
\Fgf8tm1.3Mrt/\Fgf8tm1.4Mrt \Tg(Msx2-cre)5Rem/0	involves: 129P2/OlaHsd * C57BL/6 * CBA * CD-1 * FVB/N	J:66266	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Hey2

Allelic Composition	Genetic Background	Reference	Phenotypes
\Hey2tm1Uts/\Hey2tm1Uts	either: (involves: 129X1/SvJ) or (involves: C57BL/6)	J:79025	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Invs

Allelic Composition	Genetic Background	Reference	Phenotypes
\Invsinv/\Invsinv	FVB/N-Invs^inv	J:48533	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Mks1

Allelic Composition	Genetic Background	Reference	Phenotypes
\Mks1avc6/\Mks1avc6	involves: C57BL/6J * FVB/N	J:163196	View
\Del(11Mpo-Chad)18Brd/\+	involves: 129S7/SvEvBrd * C57BL/6	J:109163	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Ntf3

Allelic Composition	Genetic Background	Reference	Phenotypes
\Ntf3tm1Par/\Ntf3tm1Par	involves: 129S1/Sv	J:35639	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Phc1

Allelic Composition	Genetic Background	Reference	Phenotypes
\Phc1tm1Os/\Phc1tm1Os	involves: 129S2/SvPas * C57BL/6	J:43764	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot

Allelic Composition	Genetic Background	Reference	Phenotypes
\Dp(16Lipi-Zbtb21)1Yey/0	involves: 129S7/SvEvBrd	J:121790	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Cytogenetic Marker: Del(11Mpo-Chad)18Brd

Allelic Composition	Genetic Background	Reference	Phenotypes
\Del(11Mpo-Chad)18Brd/\+	involves: 129S7/SvEvBrd * C57BL/6	J:109163	View

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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