tetralogy of Fallot Disease Ontology Browser

Disease Ontology Browser

tetralogy of Fallot (DOID:6419)
Alliance: disease page
Synonyms: Ventricular septal defect with pulmonary stenosis or atresia, dextraposition of aorta, and hypertrophy of right ventricle
Alt IDs: OMIM:187500, ICD10CM:Q21.3, ICD9CM:745.2, MESH:D013771, NCI:C84505, UMLS_CUI:C0039685

Term Browser
Genes (25)
Models (17)

Disease References using Mouse Models (15)

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Gja5

Allelic Composition	Genetic Background	Reference	Phenotypes
Gja5tm1Paul/Gja5tm1Paul	involves: 129S4/SvJae * C57BL/6	J:109301	View
Gja5tm1Paul/Gja5+	involves: 129S4/SvJae * C57BL/6	J:109301	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Nkx2-5

Allelic Composition	Genetic Background	Reference	Phenotypes
Nkx2-5tm2.1Mwc/Nkx2-5+	B6J.Cg-Nkx2-5^tm2.1Mwc/Mwc	J:239808	View
Nkx2-5tm3.1Mwc/Nkx2-5+	B6J.Cg-Nkx2-5^tm3.1Mwc/Mwc	J:239808	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Zfpm2

Allelic Composition	Genetic Background	Reference	Phenotypes
Zfpm2tm1Sho/Zfpm2tm1Sho	involves: 129S1/Sv	J:62879, J:78688	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Bmp10

Allelic Composition	Genetic Background	Reference	Phenotypes
Bmp10b2b2711Clo/Bmp10b2b2711Clo	C57BL/6J-Bmp10^b2b2711Clo	J:175213	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Cited2

Allelic Composition	Genetic Background	Reference	Phenotypes
Cited2tm1Ycy/Cited2tm1Ycy	involves: C57BL/6J	J:78364	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Dnah5

Allelic Composition	Genetic Background	Reference	Phenotypes
Dnah5hlb612/Dnah5hlb612	involves: C57BL/6J	J:130755	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Dock1

Allelic Composition	Genetic Background	Reference	Phenotypes
Dock1b2b3190Clo/Dock1b2b3190Clo	C57BL/6J-Dock1^b2b3190Clo	J:175213	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Fgf8

Allelic Composition	Genetic Background	Reference	Phenotypes
Fgf8tm1.3Mrt/Fgf8tm1.4Mrt Tg(Msx2-cre)5Rem/0	involves: 129P2/OlaHsd	J:66266	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Hey2

Allelic Composition	Genetic Background	Reference	Phenotypes
Hey2tm1Uts/Hey2tm1Uts	either: (involves: 129X1/SvJ) or (involves: C57BL/6)	J:79025	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Invs

Allelic Composition	Genetic Background	Reference	Phenotypes
Invsinv/Invsinv	FVB/N-Invs^inv	J:48533	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Mks1

Allelic Composition	Genetic Background	Reference	Phenotypes
Mks1avc6/Mks1avc6	involves: C57BL/6J * FVB/N	J:163196	View
Del(11Mpo-Chad)18Brd/+	involves: 129S7/SvEvBrd * C57BL/6	J:109163	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Ntf3

Allelic Composition	Genetic Background	Reference	Phenotypes
Ntf3tm1Par/Ntf3tm1Par	involves: 129S1/Sv	J:35639	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Phc1

Allelic Composition	Genetic Background	Reference	Phenotypes
Phc1tm1Os/Phc1tm1Os	involves: 129S2/SvPas * C57BL/6	J:43764	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot

Allelic Composition	Genetic Background	Reference	Phenotypes
Dp(16Lipi-Zbtb21)1Yey/0	involves: 129S7/SvEvBrd	J:121790	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Cytogenetic Marker: Del(11Mpo-Chad)18Brd

Allelic Composition	Genetic Background	Reference	Phenotypes
Del(11Mpo-Chad)18Brd/+	involves: 129S7/SvEvBrd * C57BL/6	J:109163	View

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Copyright, and Privacy Statement Send questions and comments to User Support.	last database update 05/30/2023 MGI 6.22