Sox9 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:308974 Guo S, et al., Trio cooperates with Myh9 to regulate neural crest-derived craniofacial development. Theranostics. 2021;11(9):4316-4334
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:8270673
Gene symbol:	Sox9
Gene name:	SRY (sex determining region Y)-box 9

Antibody:	anti-Sox9 (E-9): sc-166505
Detection system:	Secondary antibody coupled to Alexa Fluor 594

Results

3F merge ©

3F Sox9 ©

Specimen 3F NT: embryonic day 9.5 (more

)
Note: Double labeled: red - Sox9; green - Trio (assay MGI:8270672).

Structure	Cell Type	Level	Pattern	Image	Note
TS15: neural tube	premigratory neural crest cell	Present	Regionally restricted	3F merge enlarged left , 3F Sox9 , 3F merge	Expressed in the dorsal neural tube.
TS15: migrating neural crest	migratory neural crest cell	Present		3F merge enlarged right , 3F merge , 3F Sox9	Expressed outside of the neural tube.

3G WT ©

Specimen 3G WT: embryonic day 9.5 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS15: 1st branchial arch	neural crest cell	Present		3G WT

3G CKO ©

Specimen 3G CKO: embryonic day 9.5; H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺, Trio^tm1Mzhu/Trio^tm1Mzhu (more

)
Note: Conditional mutant.

Structure	Cell Type	Level	Pattern	Image	Note
TS15: 1st branchial arch	neural crest cell	Present		3G CKO	Decreased neural crest cells distribution compared with the control.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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