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Gene Expression Data
Assay Details
Assay
Reference: J:204287 Stegeman S, et al., Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFbeta-mediated axonogenesis. PLoS One. 2013;8(7):e68287
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8209718
Gene symbol: Nefm
Gene name: neurofilament, medium polypeptide
Results
Specimen 2A: embryonic day 18.5; Usp9xtm1Tuv/Y (more )
Structure Level Pattern Image Note
TS26: telencephalon Present Regionally restricted 2A Expression in axonal projections from entorhinal cortex to hippocampus.
Specimen 2B: embryonic day 18.5; Usp9xtm1Tuv/Y, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: telencephalon Present Regionally restricted 2B No expression in axonal projections from entorhinal cortex to hippocampus.
Specimen 3A: postnatal adult; Usp9xtm1Tuv/Y (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present Regionally restricted 3A Expression in neuronal processes.
Specimen 3B: postnatal adult; Emx1tm1(cre)Ito/Emx1+, Usp9xtm1Tuv/Y (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cerebral cortex Present Regionally restricted 3B Expression in aberrant neural processes, much thicker and oriented toward pial surface, rather than towards ventricle.
Specimen 3C: postnatal adult; Usp9xtm1Tuv/Y (more )
Note: Double labeled: red - Nefm; green - Map2 (assay MGI:8209720).
Structure Level Pattern Image Note
TS28: cerebral cortex Present Regionally restricted 3C Little overlap in expression with Map2.
Specimen 3D: postnatal adult; Emx1tm1(cre)Ito/Emx1+, Usp9xtm1Tuv/Y (more )
Note: Conditional mutant. Double labeled: red - Nefm; green - Map2 (assay MGI:8209720).
Structure Level Pattern Image Note
TS28: cerebral cortex Present Regionally restricted 3D Expression colocalized with Map2 in thick projections in cortical neurons.
Specimen 3E: postnatal adult; Usp9xtm1Tuv/Y (more )
Note: Double labeled: red - Nefm; green - Map2 (assay MGI:8209720).
Structure Level Pattern Image Note
TS28: cerebral cortex Present Regionally restricted 3E Little overlap in expression with Map2.
Specimen 3F: postnatal adult; Emx1tm1(cre)Ito/Emx1+, Usp9xtm1Tuv/Y (more )
Note: Conditional mutant. Double labeled: red - Nefm; green - Map2 (assay MGI:8209720).
Structure Level Pattern Image Note
TS28: cerebral cortex Present Regionally restricted 3F Expression colocalized with Map2 in thick projections in cortical neurons.
Specimen 4E: postnatal adult; Usp9xtm1Tuv/Y (more )
Structure Level Pattern Image Note
TS28: corpus callosum Present 4E
Specimen 4F: postnatal adult; Emx1tm1(cre)Ito/Emx1+, Usp9xtm1Tuv/Y (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: corpus callosum Weak Regionally restricted 4F Expression reduced compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/06/2026
MGI 6.29 		The Jackson Laboratory