Usp9x^tm1Tuv
Targeted Allele Detail

Summary

• Symbol: Usp9x^tm1Tuv
• Name: ubiquitin specific peptidase 9, X chromosome; targeted mutation 1, David A Tuveson
• MGI ID: MGI:5438072
• Synonyms: Usp9x^fl, Usp9x^loxP
• Gene: Usp9x Location: ChrX:12937737-13039567 bp, + strand Genetic Position: ChrX, 7.95 cM
• Alliance: Usp9x^tm1Tuv page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:186717
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 3. (J:186717)

Disease models

Expression

In Mice Carrying this Mutation:	15 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Usp9x^tm1Tuv

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Usp9x Mutation: 24 strains or lines available

References

• Original: J:186717 Perez-Mancera PA, et al., The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma. Nature. 2012 Jun 14;486(7402):266-70
• All: 11 reference(s)